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Gene: SEC61B (SEC61 translocon subunit beta) Homo sapiens
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Symbol: SEC61B
Name: SEC61 translocon subunit beta
Description: Exhibits epidermal growth factor binding activity. Predicted to contribute to P-P-bond-hydrolysis-driven protein transmembrane transporter activity. Involved in retrograde protein transport, ER to cytosol and ubiquitin-dependent ERAD pathway. Localizes to the endoplasmic reticulum and membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: protein translocation complex beta; protein transport protein SEC61 beta subunit; protein transport protein Sec61 subunit beta; Sec61 beta subunit; Sec61 complex, beta subunit; SEC61 translocon beta subunit
Orthologs:
Mus musculus (house mouse) : Sec61b (Sec61 beta subunit)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sec61b (SEC61 translocon subunit beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sec61b (SEC61 translocon beta subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : SEC61B (SEC61 translocon beta subunit)
Canis lupus familiaris (dog) : SEC61B (SEC61 translocon beta subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sec61b (SEC61 translocon beta subunit)
Sus scrofa (pig) : SEC61B (SEC61 translocon beta subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38999,222,282 - 99,230,615 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379101,984,570 - 101,992,901 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369101,024,391 - 101,032,722 (+)NCBINCBI36hg18NCBI36
Build 34999,064,124 - 99,072,455NCBI
Celera972,498,433 - 72,506,764 (+)NCBI
Cytogenetic Map9q22.33NCBI
HuRef971,583,219 - 71,591,550 (+)NCBIHuRef
CHM1_19102,131,019 - 102,139,349 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SEC61B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312761
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-03
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.