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Gene: Pknox1 (Pbx/knotted 1 homeobox) Mus musculus
Symbol: Pknox1
Name: Pbx/knotted 1 homeobox
CRRD ID: 1312772
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including angiogenesis; hemopoiesis; and positive regulation of transcription by RNA polymerase II. Localizes to cytoplasm; nucleus; and transcription regulator complex. Is expressed in several structures, including alimentary system; branchial arch; genitourinary system; nervous system; and sensory organ. Orthologous to human PKNOX1 (PBX/knotted 1 homeobox 1); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D17Wsu76; D17Wsu76e; homeobox protein PKNOX1; PBX/knotted homeobox 1; PR; PREP1
Homo sapiens (human) : PKNOX1 (PBX/knotted 1 homeobox 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pknox1 (PBX/knotted 1 homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pknox1 (PBX/knotted 1 homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PKNOX1 (PBX/knotted 1 homeobox 1)
Canis lupus familiaris (dog) : PKNOX1 (PBX/knotted 1 homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pknox1 (PBX/knotted 1 homeobox 1)
Sus scrofa (pig) : PKNOX1 (PBX/knotted 1 homeobox 1)
Chlorocebus sabaeus (African green monkey) : PKNOX1 (PBX/knotted 1 homeobox 1)
Heterocephalus glaber (naked mole-rat) : Pknox1 (PBX/knotted 1 homeobox 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391731,783,688 - 31,826,667 (+)NCBI
GRCm381731,564,722 - 31,607,693 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1731,564,734 - 31,607,693 (+)EnsemblGRCm38mm10GRCm38
MGSCv371731,701,718 - 31,744,638 (+)NCBIGRCm37mm9NCBIm37
MGSCv361731,312,406 - 31,336,394 (+)NCBImm8
Celera1732,499,119 - 32,525,010 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1716.78NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pknox1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312772
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.