Gene: HEYL (hes related family bHLH transcription factor with YRPW motif like) Homo sapiens
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Symbol: HEYL
Name: hes related family bHLH transcription factor with YRPW motif like
Description: This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bHLHb33; class B basic helix-loop-helix protein 33; hairy-related transcription factor 3; hairy/enhancer-of-split related with YRPW motif 3; hairy/enhancer-of-split related with YRPW motif-like protein; hes related family bHLH transcription factor with YRPW motif-like; hes-related family bHLH transcription factor with YRPW motif-like; HESR3; HEY-like protein; HEY3; hHeyL; hHRT3; HRT-3; HRT3; MGC12623
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38139,623,431 - 39,639,676 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37140,089,103 - 40,105,348 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36139,861,690 - 39,877,935 (-)NCBINCBI36hg18NCBI36
Build 34139,758,917 - 39,774,411NCBI
Celera138,370,855 - 38,387,100 (-)NCBI
Cytogenetic Map1p34.2NCBI
HuRef138,207,488 - 38,223,733 (-)NCBIHuRef
CHM1_1140,204,476 - 40,220,725 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on HEYL
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312805
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-05-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.