Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Tnfsf18 (tumor necrosis factor (ligand) superfamily, member 18) Mus musculus
Symbol: Tnfsf18
Name: tumor necrosis factor (ligand) superfamily, member 18
Description: Exhibits identical protein binding activity and tumor necrosis factor receptor superfamily binding activity. Involved in several processes, including positive regulation of protein homodimerization activity; regulation of T cell activation; and regulation of leukocyte chemotaxis. Localizes to the cell surface. Orthologous to human TNFSF18 (TNF superfamily member 18); INTERACTS WITH carbon nanotube; dexamethasone; lipopolysaccharide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GITR ligand; Gitrl; glucocorticoid-induced TNF-related ligand; glucocorticoid-induced-tumor necrosis factor receptor ligand; Tnlg2a; tumor necrosis factor ligand 2a; tumor necrosis factor ligand superfamily member 18
Homo sapiens (human) : TNFSF18 (TNF superfamily member 18)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tnfsf18 (TNF superfamily member 18)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnfsf18 (TNF superfamily member 18)
Pan paniscus (bonobo/pygmy chimpanzee) : TNFSF18 (TNF superfamily member 18)
Canis lupus familiaris (dog) : TNFSF18 (TNF superfamily member 18)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfsf18 (TNF superfamily member 18)
Sus scrofa (pig) : TNFSF18 (TNF superfamily member 18)
Chlorocebus sabaeus (green monkey) : TNFSF18 (TNF superfamily member 18)
Heterocephalus glaber (naked mole-rat) : Tnfsf18 (TNF superfamily member 18)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1161,494,655 - 161,505,290 (+)Ensembl
GRCm381161,494,657 - 161,505,290 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371163,424,788 - 163,435,421 (+)NCBIGRCm37mm9NCBIm37
MGSCv361163,331,332 - 163,341,967 (+)NCBImm8
Celera1163,943,104 - 163,953,733 (+)NCBICelera
Cytogenetic Map1 H2.1NCBI
cM Map169.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tnfsf18
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312876
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.