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Gene: RO60 (Ro60, Y RNA binding protein) Homo sapiens
Symbol: RO60
Name: Ro60, Y RNA binding protein
Description: Exhibits RNA binding activity. Involved in cellular response to interferon-alpha and regulation of gene expression. Localizes to the cytosol; nucleoplasm; and ribonucleoprotein complex; PARTICIPATES IN systemic lupus erythematosus pathway; INTERACTS WITH 2-methylcholine; aflatoxin B1; arsane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 60 kDa ribonucleoprotein Ro; 60 kDa SS-A/Ro ribonucleoprotein; gastric cancer multi-drug resistance protein; Ro/SSA 60kDa; ro60 autoantigen; RORNP; sjoegren syndrome type A antigen; Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-A/Ro); sjogren syndrome antigen a2 (60kda, ribonucleoprotein autoantigen ss-a/ro); SSA2; TROVE domain family member 2; TROVE domain family, member 2; TROVE2
Mus musculus (house mouse) : Ro60 (Ro60, Y RNA binding protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ro60 (Ro60, Y RNA binding protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ro60 (Ro60, Y RNA binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : RO60 (Ro60, Y RNA binding protein)
Canis lupus familiaris (dog) : RO60 (Ro60, Y RNA binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ro60 (Ro60, Y RNA binding protein)
Sus scrofa (pig) : RO60 (Ro60, Y RNA binding protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381193,059,454 - 193,091,777 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371193,028,552 - 193,060,907 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361191,295,376 - 191,327,530 (+)NCBINCBI36hg18NCBI36
Build 341189,760,820 - 189,786,771NCBI
Celera1166,138,163 - 166,170,512 (+)NCBI
Cytogenetic Map1q31.2NCBI
HuRef1164,264,353 - 164,296,702 (+)NCBIHuRef
CHM1_11194,450,271 - 194,482,819 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RO60
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312904
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.