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Gene: RO60 (Ro60, Y RNA binding protein) Homo sapiens
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Symbol: RO60
Name: Ro60, Y RNA binding protein
Description: Exhibits RNA binding activity. Involved in cellular response to interferon-alpha and regulation of gene expression. Localizes to the cytosol; nucleoplasm; and ribonucleoprotein complex; PARTICIPATES IN systemic lupus erythematosus pathway; INTERACTS WITH 2-methylcholine; aflatoxin B1; arsane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 60 kDa ribonucleoprotein Ro; 60 kDa SS-A/Ro ribonucleoprotein; gastric cancer multi-drug resistance protein; Ro/SSA 60kDa; ro60 autoantigen; RORNP; sjoegren syndrome type A antigen; Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-A/Ro); sjogren syndrome antigen a2 (60kda, ribonucleoprotein autoantigen ss-a/ro); SSA2; TROVE domain family member 2; TROVE domain family, member 2; TROVE2
Orthologs:
Mus musculus (house mouse) : Ro60 (Ro60, Y RNA binding protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ro60 (Ro60, Y RNA binding protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ro60 (Ro60, Y RNA binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : RO60 (Ro60, Y RNA binding protein)
Canis lupus familiaris (dog) : RO60 (Ro60, Y RNA binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ro60 (Ro60, Y RNA binding protein)
Sus scrofa (pig) : RO60 (Ro60, Y RNA binding protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381193,059,454 - 193,091,777 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371193,028,552 - 193,060,907 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361191,295,376 - 191,327,530 (+)NCBINCBI36hg18NCBI36
Build 341189,760,820 - 189,786,771NCBI
Celera1166,138,163 - 166,170,512 (+)NCBI
Cytogenetic Map1q31.2NCBI
HuRef1164,264,353 - 164,296,702 (+)NCBIHuRef
CHM1_11194,450,271 - 194,482,819 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RO60
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312904
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.