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Gene: MSRB1 (methionine sulfoxide reductase B1) Homo sapiens
Symbol: MSRB1
Name: methionine sulfoxide reductase B1
Description: Predicted to have actin binding activity; peptide-methionine (R)-S-oxide reductase activity; and zinc ion binding activity. Predicted to be involved in actin filament polymerization; innate immune response; and protein repair. Localizes to the nucleoplasm. Predicted to colocalize with the actin cytoskeleton.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HSPC270; methionine sulfoxide reductase; methionine-R-sulfoxide reductase B1; MGC3344; selenoprotein R; selenoprotein X, 1; SELR; SELX; SepR; SEPX1
Mus musculus (house mouse) : Msrb1 (methionine sulfoxide reductase B1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Msrb1 (methionine sulfoxide reductase B1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Msrb1 (methionine sulfoxide reductase B1)
Pan paniscus (bonobo/pygmy chimpanzee) : MSRB1 (methionine sulfoxide reductase B1)
Canis lupus familiaris (dog) : MSRB1 (methionine sulfoxide reductase B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Msrb1 (methionine sulfoxide reductase B1)
Sus scrofa (pig) : MSRB1 (methionine sulfoxide reductase B1)
more info ...
Related Pseudogenes: MSRB1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38161,938,229 - 1,943,326 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37161,988,234 - 1,993,294 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36161,928,235 - 1,933,295 (-)NCBINCBI36hg18NCBI36
Build 34161,928,234 - 1,933,295NCBI
Celera162,200,442 - 2,205,502 (-)NCBI
Cytogenetic Map16p13.3NCBI
HuRef161,912,836 - 1,917,896 (-)NCBIHuRef
CHM1_1161,988,182 - 1,993,242 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MSRB1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312916
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.