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Gene: SMYD1 (SET and MYND domain containing 1) Homo sapiens
Symbol: SMYD1
Name: SET and MYND domain containing 1
Description: Predicted to have several functions, including histone-lysine N-methyltransferase activity; metal ion binding activity; and transcription corepressor activity. Involved in positive regulation of myoblast differentiation and positive regulation of myotube differentiation. Predicted to localize to the cytoplasm and nucleus; PARTICIPATES IN histone modification pathway; INTERACTS WITH 17beta-estradiol; doxorubicin; sunitinib.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BOP; CD8 beta opposite; histone-lysine N-methyltransferase SMYD1; KMT3D; SET and MYND domain-containing protein 1; zinc finger, MYND domain containing 18; ZMYND18; ZMYND22
Mus musculus (house mouse) : Smyd1 (SET and MYND domain containing 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Smyd1 (SET and MYND domain containing 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smyd1 (SET and MYND domain containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SMYD1 (SET and MYND domain containing 1)
Canis lupus familiaris (dog) : SMYD1 (SET and MYND domain containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smyd1 (SET and MYND domain containing 1)
Sus scrofa (pig) : SMYD1 (SET and MYND domain containing 1)
Chlorocebus sabaeus (African green monkey) : SMYD1 (SET and MYND domain containing 1)
Heterocephalus glaber (naked mole-rat) : Smyd1 (SET and MYND domain containing 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl288,067,825 - 88,113,384 (+)EnsemblGRCh38hg38GRCh38
GRCh38288,067,825 - 88,113,384 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37288,367,299 - 88,412,906 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36288,148,497 - 88,194,018 (+)NCBINCBI36hg18NCBI36
Celera288,373,097 - 88,418,568 (-)NCBI
Cytogenetic Map2p11.2NCBI
HuRef287,289,577 - 87,335,154 (+)NCBIHuRef
CHM1_1288,296,599 - 88,342,189 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SMYD1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312941
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.