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Gene: ARHGEF12 (Rho guanine nucleotide exchange factor 12) Homo sapiens
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Symbol: ARHGEF12
Name: Rho guanine nucleotide exchange factor 12
Description: Exhibits G protein-coupled receptor binding activity. Involved in G protein-coupled receptor signaling pathway. Localizes to the cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp686O2372; KIAA0382; LARG; leukemia-associated rho guanine nucleotide exchange factor; leukemia-associated RhoGEF; PRO2792; Rho guanine nucleotide exchange factor (GEF) 12
Orthologs:
Mus musculus (house mouse) : Arhgef12 (Rho guanine nucleotide exchange factor (GEF) 12)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arhgef12 (Rho guanine nucleotide exchange factor 12)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arhgef12 (Rho guanine nucleotide exchange factor 12)
Pan paniscus (bonobo/pygmy chimpanzee) : ARHGEF12 (Rho guanine nucleotide exchange factor 12)
Canis lupus familiaris (dog) : ARHGEF12 (Rho guanine nucleotide exchange factor 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arhgef12 (Rho guanine nucleotide exchange factor 12)
Sus scrofa (pig) : ARHGEF12 (Rho guanine nucleotide exchange factor 12)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl11120,336,413 - 120,489,937 (+)Ensembl
GRCh3811120,336,276 - 120,489,937 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711120,207,264 - 120,360,645 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611119,713,156 - 119,865,855 (+)NCBINCBI36hg18NCBI36
Build 3411119,713,155 - 119,865,855NCBI
Celera11117,367,395 - 117,520,075 (+)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11116,148,609 - 116,301,456 (+)NCBIHuRef
CHM1_111120,095,071 - 120,248,048 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ARHGEF12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312950
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.