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Gene: POLG2 (DNA polymerase gamma 2, accessory subunit) Homo sapiens
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Symbol: POLG2
Name: DNA polymerase gamma 2, accessory subunit
Description: Predicted to have DNA-directed DNA polymerase activity. Involved in DNA-dependent DNA replication. Localizes to the gamma DNA polymerase complex and mitochondrial nucleoid. Implicated in chronic progressive external ophthalmoplegia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DNA polymerase gamma accessory 55 kDa subunit; DNA polymerase subunit gamma-2, mitochondrial; HP55; mitochondrial DNA polymerase accessory subunit; mitochondrial DNA polymerase subunit gamma-2; mitochondrial DNA polymerase, accessory subunit; MTDPS16; MTPOLB; p55; PEOA4; POLB; POLG-BETA; POLGB; polymerase (DNA directed), gamma 2, accessory subunit; polymerase (DNA) gamma 2, accessory subunit
Orthologs:
Mus musculus (house mouse) : Polg2 (polymerase (DNA directed), gamma 2, accessory subunit)  MGI  Alliance
Rattus norvegicus (Norway rat) : Polg2 (DNA polymerase gamma 2, accessory subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Polg2 (DNA polymerase gamma 2, accessory subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : POLG2 (DNA polymerase gamma 2, accessory subunit)
Canis lupus familiaris (dog) : POLG2 (DNA polymerase gamma 2, accessory subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Polg2 (DNA polymerase gamma 2, accessory subunit)
Sus scrofa (pig) : POLG2 (DNA polymerase gamma 2, accessory subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1764,477,785 - 64,497,054 (-)Ensembl
GRCh381764,477,785 - 64,497,054 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371762,473,902 - 62,493,184 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361759,904,364 - 59,923,631 (-)NCBINCBI36hg18NCBI36
Build 341759,904,364 - 59,923,604NCBI
Celera1756,943,739 - 56,963,326 (-)NCBI
Cytogenetic Map17q23.3NCBI
HuRef1757,923,123 - 57,942,249 (-)NCBIHuRef
CHM1_11762,537,826 - 62,557,108 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on POLG2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312978
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.