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Gene: TWF2 (twinfilin actin binding protein 2) Homo sapiens
Symbol: TWF2
Name: twinfilin actin binding protein 2
CRRD ID: 1312984
Description: Exhibits ATP binding activity and protein kinase C binding activity. Involved in several processes, including cellular response to retinoic acid; positive regulation of cell projection organization; and regulation of actin cytoskeleton organization. Localizes to cytoplasm and growth cone.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A6-related protein; A6r; A6RP; FLJ56277; hA6RP; MSTP011; protein tyrosine kinase 9-like (A6-related protein); PTK9L; PTK9L protein tyrosine kinase 9-like (A6-related protein); twinfilin actin-binding protein 2; twinfilin, actin-binding protein, homolog 2; twinfilin-1-like protein; twinfilin-2
Mus musculus (house mouse) : Twf2 (twinfilin actin binding protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Twf2 (twinfilin actin-binding protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Twf2 (twinfilin actin binding protein 2)
Canis lupus familiaris (dog) : TWF2 (twinfilin actin binding protein 2)
Sus scrofa (pig) : TWF2 (twinfilin actin binding protein 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl352,228,612 - 52,239,158 (-)EnsemblGRCh38hg38GRCh38
GRCh38352,228,612 - 52,239,158 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37352,262,626 - 52,273,183 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,237,666 - 52,248,223 (-)NCBINCBI36hg18NCBI36
Build 34352,237,666 - 52,248,223NCBI
Celera352,241,938 - 52,252,496 (-)NCBI
Cytogenetic Map3p21.2NCBI
HuRef352,324,788 - 52,335,347 (-)NCBIHuRef
CHM1_1352,215,154 - 52,225,723 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TWF2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312984
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.