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Gene: Wdr5 (WD repeat domain 5) Mus musculus
Symbol: Wdr5
Name: WD repeat domain 5
CRRD ID: 1313023
Description: Predicted to contribute to H4 histone acetyltransferase activity and histone methyltransferase activity (H3-K4 specific). Involved in histone H3-K4 methylation; positive regulation of gluconeogenesis; and skeletal system development. Localizes to Ada2/Gcn5/Ada3 transcription activator complex. Is expressed in cerebral cortex; testis; and vault of skull. Orthologous to human WDR5 (WD repeat domain 5); PARTICIPATES IN histone modification pathway; RNA polymerase II transcription initiation pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410008O07Rik; AA408785; AA960360; Big; Big-; Big-3; BMP2-induced 3-kb gene protein; WD repeat-containing protein 5; WD repeat-containing protein BIG-3
Homo sapiens (human) : WDR5 (WD repeat domain 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Wdr5 (WD repeat domain 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wdr5 (WD repeat domain 5)
Pan paniscus (bonobo/pygmy chimpanzee) : WDR5 (WD repeat domain 5)
Canis lupus familiaris (dog) : WDR5 (WD repeat domain 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wdr5 (WD repeat domain 5)
Sus scrofa (pig) : WDR5 (WD repeat domain 5)
Chlorocebus sabaeus (African green monkey) : WDR5 (WD repeat domain 5)
Heterocephalus glaber (naked mole-rat) : Wdr5 (WD repeat domain 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39227,405,159 - 27,426,547 (+)NCBI
GRCm38227,515,147 - 27,536,535 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl227,515,157 - 27,536,535 (+)EnsemblGRCm38mm10GRCm38
MGSCv37227,370,667 - 27,392,055 (+)NCBIGRCm37mm9NCBIm37
MGSCv36227,337,223 - 27,358,544 (+)NCBImm8
Celera227,217,888 - 27,239,293 (+)NCBICelera
Cytogenetic Map2A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Wdr5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313023
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.