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Gene: Wdr5 (WD repeat domain 5) Mus musculus
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Symbol: Wdr5
Name: WD repeat domain 5
CRRD ID: 1313023
Description: Predicted to contribute to H4 histone acetyltransferase activity and histone methyltransferase activity (H3-K4 specific). Involved in histone H3-K4 methylation; positive regulation of gluconeogenesis; and skeletal system development. Localizes to Ada2/Gcn5/Ada3 transcription activator complex. Is expressed in cerebral cortex; testis; and vault of skull. Orthologous to human WDR5 (WD repeat domain 5); PARTICIPATES IN histone modification pathway; RNA polymerase II transcription initiation pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410008O07Rik; AA408785; AA960360; Big; Big-; Big-3; BMP2-induced 3-kb gene protein; WD repeat-containing protein 5; WD repeat-containing protein BIG-3
Orthologs:
Homo sapiens (human) : WDR5 (WD repeat domain 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Wdr5 (WD repeat domain 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wdr5 (WD repeat domain 5)
Pan paniscus (bonobo/pygmy chimpanzee) : WDR5 (WD repeat domain 5)
Canis lupus familiaris (dog) : WDR5 (WD repeat domain 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wdr5 (WD repeat domain 5)
Sus scrofa (pig) : WDR5 (WD repeat domain 5)
Chlorocebus sabaeus (African green monkey) : WDR5 (WD repeat domain 5)
Heterocephalus glaber (naked mole-rat) : Wdr5 (WD repeat domain 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39227,405,159 - 27,426,547 (+)NCBI
GRCm38227,515,147 - 27,536,535 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl227,515,157 - 27,536,535 (+)EnsemblGRCm38mm10GRCm38
MGSCv37227,370,667 - 27,392,055 (+)NCBIGRCm37mm9NCBIm37
MGSCv36227,337,223 - 27,358,544 (+)NCBImm8
Celera227,217,888 - 27,239,293 (+)NCBICelera
Cytogenetic Map2A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Wdr5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313023
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.