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Gene: NRL (neural retina leucine zipper) Homo sapiens
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Symbol: NRL
Name: neural retina leucine zipper
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; leucine zipper domain binding activity; and transcription coactivator activity. Involved in positive regulation of transcription by RNA polymerase II. Localizes to the cytosol and nucleoplasm. Implicated in retinitis pigmentosa and retinitis pigmentosa 27.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: D14S46E; neural retina-specific leucine zipper protein; neural retinal-specific leucine zipper; NRL-MAF; RP27
Orthologs:
Mus musculus (house mouse) : Nrl (neural retina leucine zipper gene)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nrl (neural retina leucine zipper)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nrl (neural retina leucine zipper)
Pan paniscus (bonobo/pygmy chimpanzee) : NRL (neural retina leucine zipper)
Canis lupus familiaris (dog) : NRL (neural retina leucine zipper)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nrl (neural retina leucine zipper)
Sus scrofa (pig) : NRL (neural retina leucine zipper)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1424,080,107 - 24,115,014 (-)Ensembl
GRCh381424,078,662 - 24,114,949 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371424,547,902 - 24,584,223 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,619,156 - 23,623,672 (-)NCBINCBI36hg18NCBI36
Build 341423,619,215 - 23,654,063NCBI
Celera144,413,793 - 4,418,309 (-)NCBI
Cytogenetic Map14q11.2-q12NCBI
HuRef144,664,249 - 4,668,765 (-)NCBIHuRef
CHM1_11424,547,991 - 24,552,507 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on NRL
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313083
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.