Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: DR1 (down-regulator of transcription 1) Homo sapiens
Symbol: DR1
Name: down-regulator of transcription 1
Description: Exhibits TBP-class protein binding activity. Involved in histone H3 acetylation. Localizes to Ada2/Gcn5/Ada3 transcription activator complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: down-regulator of transcription 1, TBP-binding (negative cofactor 2); NC2; NC2-BETA; NC2B; NCB2; negative cofactor 2; negative cofactor 2 beta; negative cofactor 2-beta; TATA-binding protein-associated phosphoprotein
Mus musculus (house mouse) : Dr1 (down-regulator of transcription 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dr1 (down-regulator of transcription 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dr1 (down-regulator of transcription 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DR1 (down-regulator of transcription 1)
Canis lupus familiaris (dog) : DR1 (down-regulator of transcription 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dr1 (down-regulator of transcription 1)
Sus scrofa (pig) : DR1 (down-regulator of transcription 1)
Chlorocebus sabaeus (African green monkey) : DR1 (down-regulator of transcription 1)
Heterocephalus glaber (naked mole-rat) : Dr1 (down-regulator of transcription 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl193,345,907 - 93,369,493 (+)EnsemblGRCh38hg38GRCh38
GRCh38193,345,907 - 93,369,493 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37193,811,478 - 93,828,149 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,584,066 - 93,600,737 (+)NCBINCBI36hg18NCBI36
Build 34193,523,498 - 93,540,167NCBI
Celera192,065,544 - 92,082,224 (+)NCBI
Cytogenetic Map1p22.1NCBI
HuRef191,933,028 - 91,949,702 (+)NCBIHuRef
CHM1_1193,926,443 - 93,943,112 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DR1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313088
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.