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Gene: SMC2 (structural maintenance of chromosomes 2) Homo sapiens
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Symbol: SMC2
Name: structural maintenance of chromosomes 2
Description: Exhibits protein heterodimerization activity. Involved in mitotic chromosome condensation. Localizes to the condensin complex; cytoplasm; and nuclear lumen; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CAP-E; CAPE; chromosome-associated protein E; FLJ10093; hCAP-E; SMC protein 2; SMC-2; SMC2 (structural maintenance of chromosomes 2, yeast)-like 1; SMC2 structural maintenance of chromosomes 2-like 1; smc2 structural maintenance of chromosomes 2-like 1 (yeast); SMC2L1; structural maintenance of chromosomes (SMC) family member, chromosome-associated protein E; structural maintenance of chromosomes protein 2; XCAP-E homolog
Orthologs:
Mus musculus (house mouse) : Smc2 (structural maintenance of chromosomes 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Smc2 (structural maintenance of chromosomes 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smc2 (structural maintenance of chromosomes 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SMC2 (structural maintenance of chromosomes 2)
Canis lupus familiaris (dog) : SMC2 (structural maintenance of chromosomes 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smc2 (structural maintenance of chromosomes 2)
Sus scrofa (pig) : SMC2 (structural maintenance of chromosomes 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389104,093,760 - 104,141,419 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379106,856,213 - 106,903,700 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369105,896,362 - 105,943,521 (+)NCBINCBI36hg18NCBI36
Build 349103,936,161 - 103,981,492NCBI
Celera977,361,453 - 77,408,608 (+)NCBI
Cytogenetic Map9q31.1NCBI
HuRef976,458,199 - 76,505,354 (+)NCBIHuRef
CHM1_19107,002,961 - 107,050,087 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on SMC2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313128
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.