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Gene: SMC2 (structural maintenance of chromosomes 2) Homo sapiens
Symbol: SMC2
Name: structural maintenance of chromosomes 2
Description: Exhibits protein heterodimerization activity. Involved in mitotic chromosome condensation. Localizes to the condensin complex; cytoplasm; and nuclear lumen; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CAP-E; CAPE; chromosome-associated protein E; FLJ10093; hCAP-E; SMC protein 2; SMC-2; SMC2 (structural maintenance of chromosomes 2, yeast)-like 1; SMC2 structural maintenance of chromosomes 2-like 1; smc2 structural maintenance of chromosomes 2-like 1 (yeast); SMC2L1; structural maintenance of chromosomes (SMC) family member, chromosome-associated protein E; structural maintenance of chromosomes protein 2; XCAP-E homolog
Mus musculus (house mouse) : Smc2 (structural maintenance of chromosomes 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Smc2 (structural maintenance of chromosomes 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smc2 (structural maintenance of chromosomes 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SMC2 (structural maintenance of chromosomes 2)
Canis lupus familiaris (dog) : SMC2 (structural maintenance of chromosomes 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smc2 (structural maintenance of chromosomes 2)
Sus scrofa (pig) : SMC2 (structural maintenance of chromosomes 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh389104,093,760 - 104,141,419 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379106,856,213 - 106,903,700 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369105,896,362 - 105,943,521 (+)NCBINCBI36hg18NCBI36
Build 349103,936,161 - 103,981,492NCBI
Celera977,361,453 - 77,408,608 (+)NCBI
Cytogenetic Map9q31.1NCBI
HuRef976,458,199 - 76,505,354 (+)NCBIHuRef
CHM1_19107,002,961 - 107,050,087 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SMC2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313128
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.