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Gene: PHF2 (PHD finger protein 2) Homo sapiens
Symbol: PHF2
Name: PHD finger protein 2
CRRD ID: 1313130
Description: Exhibits several functions, including histone demethylase activity (H3-K9 specific); transcription coactivator activity; and transition metal ion binding activity. Involved in negative regulation of ribosomal DNA heterochromatin assembly and protein demethylation. Localizes to kinetochore; nucleolus; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CENP-35; centromere protein 35; GRC5; JHDM1E; jumonji C domain-containing histone demethylase 1E; KDM7C; KIAA0662; lysine-specific demethylase PHF2; MGC176680
Mus musculus (house mouse) : Phf2 (PHD finger protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Phf2 (PHD finger protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Phf2 (PHD finger protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PHF2 (PHD finger protein 2)
Canis lupus familiaris (dog) : PHF2 (PHD finger protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Phf2 (PHD finger protein 2)
Sus scrofa (pig) : PHF2 (PHD finger protein 2)
Chlorocebus sabaeus (African green monkey) : PHF2 (PHD finger protein 2)
Heterocephalus glaber (naked mole-rat) : Phf2 (PHD finger protein 2)
more info ...
Related Pseudogenes: PHF2P1   PHF2P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl993,576,584 - 93,679,587 (+)EnsemblGRCh38hg38GRCh38
GRCh38993,576,584 - 93,679,587 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37996,338,909 - 96,441,869 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36995,378,730 - 95,481,690 (+)NCBINCBI36hg18NCBI36
Celera966,780,357 - 66,883,454 (+)NCBI
Cytogenetic Map9q22.31NCBI
HuRef966,069,283 - 66,118,414 (+)NCBIHuRef
CHM1_1996,485,947 - 96,588,795 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PHF2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313130
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.