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Gene: PHF2 (PHD finger protein 2) Homo sapiens
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Symbol: PHF2
Name: PHD finger protein 2
Description: Exhibits histone demethylase activity (H3-K9 specific); methylated histone binding activity; and transition metal ion binding activity. Contributes to transcription coactivator activity. Involved in negative regulation of chromatin silencing at rDNA and protein demethylation. Localizes to the kinetochore; nucleolus; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CENP-35; centromere protein 35; GRC5; JHDM1E; jumonji C domain-containing histone demethylase 1E; KDM7C; KIAA0662; lysine-specific demethylase PHF2; MGC176680
Orthologs:
Mus musculus (house mouse) : Phf2 (PHD finger protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Phf2 (PHD finger protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Phf2 (PHD finger protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PHF2 (PHD finger protein 2)
Canis lupus familiaris (dog) : PHF2 (PHD finger protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Phf2 (PHD finger protein 2)
Sus scrofa (pig) : PHF2 (PHD finger protein 2)
more info ...
Related Pseudogenes: PHF2P1   PHF2P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38993,576,584 - 93,679,587 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37996,338,909 - 96,441,869 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36995,378,730 - 95,481,690 (+)NCBINCBI36hg18NCBI36
Celera966,780,357 - 66,883,454 (+)NCBI
Cytogenetic Map9q22.31NCBI
HuRef966,069,283 - 66,118,414 (+)NCBIHuRef
CHM1_1996,485,947 - 96,588,795 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PHF2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313130
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.