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Gene: Phf2 (PHD finger protein 2) Mus musculus
Symbol: Phf2
Name: PHD finger protein 2
CRRD ID: 1313131
Description: Predicted to have several functions, including histone demethylase activity (H3-K9 specific); transcription coactivator activity; and transition metal ion binding activity. Involved in histone H3-K9 demethylation. Predicted to localize to kinetochore; nucleolus; and nucleoplasm. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and respiratory system. Orthologous to human PHF2 (PHD finger protein 2); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; ethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GRC5; lysine-specific demethylase PHF2
Homo sapiens (human) : PHF2 (PHD finger protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Phf2 (PHD finger protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Phf2 (PHD finger protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PHF2 (PHD finger protein 2)
Canis lupus familiaris (dog) : PHF2 (PHD finger protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Phf2 (PHD finger protein 2)
Sus scrofa (pig) : PHF2 (PHD finger protein 2)
Chlorocebus sabaeus (African green monkey) : PHF2 (PHD finger protein 2)
Heterocephalus glaber (naked mole-rat) : Phf2 (PHD finger protein 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391348,955,226 - 49,024,361 (-)NCBI
GRCm381348,801,750 - 48,870,885 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1348,801,750 - 48,871,119 (-)EnsemblGRCm38mm10GRCm38
MGSCv371348,897,119 - 48,966,254 (-)NCBIGRCm37mm9NCBIm37
MGSCv361348,813,687 - 48,882,820 (-)NCBImm8
Celera1349,891,719 - 49,925,245 (-)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1324.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Phf2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313131
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.