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Gene: Havcr2 (hepatitis A virus cellular receptor 2) Mus musculus
Symbol: Havcr2
Name: hepatitis A virus cellular receptor 2
Description: Predicted to have metal ion binding activity. Involved in several processes, including negative regulation of cytokine production; regulation of defense response; and regulation of leukocyte activation. Localizes to the cell surface; early endosome; and immunological synapse. Human ortholog(s) of this gene implicated in renal cell carcinoma. Is expressed in several structures, including colon; dorsal aorta; liver; lung; and reproductive system. Orthologous to human HAVCR2 (hepatitis A virus cellular receptor 2); INTERACTS WITH (+)-catechin; benzo[a]pyrene; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HAVcr-2; hepatitis A virus cellular receptor 2 homolog; MGC124149; MGC124150; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; TIM-3; Tim3; TIMD-3; Timd3
Homo sapiens (human) : HAVCR2 (hepatitis A virus cellular receptor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Havcr2 (hepatitis A virus cellular receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Havcr2 (hepatitis A virus cellular receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HAVCR2 (hepatitis A virus cellular receptor 2)
Canis lupus familiaris (dog) : HAVCR2 (hepatitis A virus cellular receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Havcr2 (hepatitis A virus cellular receptor 2)
Sus scrofa (pig) : HAVCR2 (hepatitis A virus cellular receptor 2)
Chlorocebus sabaeus (African green monkey) : HAVCR2 (hepatitis A virus cellular receptor 2)
Heterocephalus glaber (naked mole-rat) : Havcr2 (hepatitis A virus cellular receptor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1146,454,935 - 46,481,255 (+)EnsemblGRCm38mm10GRCm38
GRCm381146,454,931 - 46,481,255 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371146,268,433 - 46,294,757 (+)NCBIGRCm37mm9NCBIm37
MGSCv361146,298,358 - 46,324,678 (+)NCBImm8
Celera1151,038,900 - 51,067,047 (+)NCBICelera
Cytogenetic Map11B1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Havcr2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313141
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.