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Gene: RNF135 (ring finger protein 135) Homo sapiens
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Symbol: RNF135
Name: ring finger protein 135
Description: Exhibits several functions, including RIG-I binding activity; identical protein binding activity; and ubiquitin protein ligase activity. Involved in several processes, including defense response to other organism; free ubiquitin chain polymerization; and protein K63-linked ubiquitination. Localizes to the cytoplasmic stress granule and ribonucleoprotein complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: E3 ubiquitin-protein ligase RNF135; L13; MGC13061; MMFD; REUL; RIG-I E3 ubiquitin ligase; RING-type E3 ubiquitin transferase RNF135; Riplet
Orthologs:
Mus musculus (house mouse) : Rnf135 (ring finger protein 135)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rnf135 (ring finger protein 135)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rnf135 (ring finger protein 135)
Pan paniscus (bonobo/pygmy chimpanzee) : RNF135 (ring finger protein 135)
Canis lupus familiaris (dog) : RNF135 (ring finger protein 135)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rnf135 (ring finger protein 135)
Sus scrofa (pig) : RNF135 (ring finger protein 135)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381730,968,642 - 30,999,911 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371729,296,224 - 29,326,929 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361726,322,082 - 26,351,053 (+)NCBINCBI36hg18NCBI36
Celera1726,218,879 - 26,247,850 (+)NCBI
Cytogenetic Map17q11.2NCBI
HuRef1725,508,635 - 25,537,506 (+)NCBIHuRef
CHM1_11729,360,522 - 29,390,158 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on RNF135
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313173
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.