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Gene: LIMS2 (LIM zinc finger domain containing 2) Homo sapiens
Symbol: LIMS2
Name: LIM zinc finger domain containing 2
Description: This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ10044; ILK-binding protein; LGMD2W; LIM and senescent cell antigen-like domains 2; LIM and senescent cell antigen-like-containing domain protein 2; LIM-like protein 2; LIM-type zinc finger domains 2; MDRCMTT; particularly interesting new Cys-His protein 2; PINCH-2; PINCH2
Mus musculus (house mouse) : Lims2 (LIM and senescent cell antigen like domains 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lims2 (LIM zinc finger domain containing 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lims2 (LIM zinc finger domain containing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : LIMS2 (LIM zinc finger domain containing 2)
Canis lupus familiaris (dog) : LIMS2 (LIM zinc finger domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lims2 (LIM zinc finger domain containing 2)
Sus scrofa (pig) : LIMS2 (LIM zinc finger domain containing 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382127,638,381 - 127,681,786 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372128,395,996 - 128,439,360 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362128,112,471 - 128,138,590 (-)NCBINCBI36hg18NCBI36
Build 342128,112,232 - 128,138,343NCBI
Celera2121,706,938 - 121,750,307 (-)NCBI
Cytogenetic Map2q14.3NCBI
HuRef2120,702,371 - 120,745,600 (-)NCBIHuRef
CHM1_12128,400,424 - 128,443,742 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LIMS2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313204
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.