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Gene: LIMS2 (LIM zinc finger domain containing 2) Homo sapiens
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Symbol: LIMS2
Name: LIM zinc finger domain containing 2
Description: This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ10044; ILK-binding protein; LGMD2W; LIM and senescent cell antigen-like domains 2; LIM and senescent cell antigen-like-containing domain protein 2; LIM-like protein 2; LIM-type zinc finger domains 2; MDRCMTT; particularly interesting new Cys-His protein 2; PINCH-2; PINCH2
Orthologs:
Mus musculus (house mouse) : Lims2 (LIM and senescent cell antigen like domains 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lims2 (LIM zinc finger domain containing 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lims2 (LIM zinc finger domain containing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : LIMS2 (LIM zinc finger domain containing 2)
Canis lupus familiaris (dog) : LIMS2 (LIM zinc finger domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lims2 (LIM zinc finger domain containing 2)
Sus scrofa (pig) : LIMS2 (LIM zinc finger domain containing 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382127,638,381 - 127,681,786 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372128,395,996 - 128,439,360 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362128,112,471 - 128,138,590 (-)NCBINCBI36hg18NCBI36
Build 342128,112,232 - 128,138,343NCBI
Celera2121,706,938 - 121,750,307 (-)NCBI
Cytogenetic Map2q14.3NCBI
HuRef2120,702,371 - 120,745,600 (-)NCBIHuRef
CHM1_12128,400,424 - 128,443,742 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on LIMS2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313204
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.