Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: ROR2 (receptor tyrosine kinase like orphan receptor 2) Homo sapiens
Symbol: ROR2
Name: receptor tyrosine kinase like orphan receptor 2
Description: Exhibits Wnt-protein binding activity and mitogen-activated protein kinase kinase kinase binding activity. Involved in negative regulation of cell population proliferation and positive regulation of cell migration. Predicted to localize to the axon; integral component of plasma membrane; and receptor complex. Implicated in autosomal recessive Robinow syndrome; brachydactyly type B1; and cleft palate.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BDB; BDB1; MGC163394; neurotrophic tyrosine kinase receptor-related 2; neurotrophic tyrosine kinase, receptor-related 2; NTRKR2; receptor tyrosine kinase-like orphan receptor 2; tyrosine-protein kinase transmembrane receptor ROR2
Mus musculus (house mouse) : Ror2 (receptor tyrosine kinase-like orphan receptor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ror2 (receptor tyrosine kinase-like orphan receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ror2 (receptor tyrosine kinase like orphan receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ROR2 (receptor tyrosine kinase like orphan receptor 2)
Canis lupus familiaris (dog) : ROR2 (receptor tyrosine kinase like orphan receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ror2 (receptor tyrosine kinase like orphan receptor 2)
Sus scrofa (pig) : ROR2 (receptor tyrosine kinase like orphan receptor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38991,722,598 - 91,950,228 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37994,484,878 - 94,712,444 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36993,524,705 - 93,752,265 (-)NCBINCBI36hg18NCBI36
Build 34991,564,438 - 91,791,999NCBI
Celera964,921,783 - 65,148,752 (-)NCBI
Cytogenetic Map9q22.31NCBI
HuRef964,163,034 - 64,390,111 (-)NCBIHuRef
CHM1_1994,631,872 - 94,858,883 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ROR2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313207
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.