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Gene: ROR2 (receptor tyrosine kinase like orphan receptor 2) Homo sapiens
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Symbol: ROR2
Name: receptor tyrosine kinase like orphan receptor 2
Description: Exhibits Wnt-protein binding activity and mitogen-activated protein kinase kinase kinase binding activity. Involved in negative regulation of cell population proliferation and positive regulation of cell migration. Predicted to localize to the axon; integral component of plasma membrane; and receptor complex. Implicated in autosomal recessive Robinow syndrome; brachydactyly type B1; and cleft palate.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BDB; BDB1; MGC163394; neurotrophic tyrosine kinase receptor-related 2; neurotrophic tyrosine kinase, receptor-related 2; NTRKR2; receptor tyrosine kinase-like orphan receptor 2; tyrosine-protein kinase transmembrane receptor ROR2
Orthologs:
Mus musculus (house mouse) : Ror2 (receptor tyrosine kinase-like orphan receptor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ror2 (receptor tyrosine kinase-like orphan receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ror2 (receptor tyrosine kinase like orphan receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ROR2 (receptor tyrosine kinase like orphan receptor 2)
Canis lupus familiaris (dog) : ROR2 (receptor tyrosine kinase like orphan receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ror2 (receptor tyrosine kinase like orphan receptor 2)
Sus scrofa (pig) : ROR2 (receptor tyrosine kinase like orphan receptor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38991,722,598 - 91,950,228 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37994,484,878 - 94,712,444 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36993,524,705 - 93,752,265 (-)NCBINCBI36hg18NCBI36
Build 34991,564,438 - 91,791,999NCBI
Celera964,921,783 - 65,148,752 (-)NCBI
Cytogenetic Map9q22.31NCBI
HuRef964,163,034 - 64,390,111 (-)NCBIHuRef
CHM1_1994,631,872 - 94,858,883 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ROR2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313207
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.