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Gene: Ror2 (receptor tyrosine kinase-like orphan receptor 2) Mus musculus
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Symbol: Ror2
Name: receptor tyrosine kinase-like orphan receptor 2
Description: Exhibits Wnt-protein binding activity; frizzled binding activity; and mitogen-activated protein kinase kinase kinase binding activity. Involved in several processes, including cell surface receptor signaling pathway; embryonic morphogenesis; and regulation of canonical Wnt signaling pathway. Predicted to localize to several cellular components, including dendrite; microtubule; and neuronal cell body. Is expressed in several structures, including embryo mesenchyme; genitourinary system; jaw; neural ectoderm; and sensory organ. Used to study autosomal recessive Robinow syndrome. Human ortholog(s) of this gene implicated in autosomal recessive Robinow syndrome; brachydactyly type B1; and cleft palate. Orthologous to human ROR2 (receptor tyrosine kinase like orphan receptor 2); PARTICIPATES IN Wnt signaling, non-canonical pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: mRor2; neurotrophic tyrosine kinase, receptor related 2; neurotrophic tyrosine kinase, receptor-related 2; Ntr; Ntrkr2; tyrosine-protein kinase transmembrane receptor ROR2
Orthologs:
Homo sapiens (human) : ROR2 (receptor tyrosine kinase like orphan receptor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ror2 (receptor tyrosine kinase-like orphan receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ror2 (receptor tyrosine kinase like orphan receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ROR2 (receptor tyrosine kinase like orphan receptor 2)
Canis lupus familiaris (dog) : ROR2 (receptor tyrosine kinase like orphan receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ror2 (receptor tyrosine kinase like orphan receptor 2)
Sus scrofa (pig) : ROR2 (receptor tyrosine kinase like orphan receptor 2)
Chlorocebus sabaeus (African green monkey) : ROR2 (receptor tyrosine kinase like orphan receptor 2)
Heterocephalus glaber (naked mole-rat) : Ror2 (receptor tyrosine kinase like orphan receptor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1353,109,312 - 53,286,124 (-)EnsemblGRCm38mm10GRCm38
GRCm381353,109,317 - 53,286,124 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371353,204,686 - 53,381,478 (-)NCBIGRCm37mm9NCBIm37
MGSCv361353,121,749 - 53,293,643 (-)NCBImm8
Celera1354,186,098 - 54,362,690 (-)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1327.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Ror2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313208
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.