Gene: POSTN (periostin) Homo sapiens
Analyze
Symbol:
POSTN
Name:
periostin
Description:
Exhibits metal ion binding activity. Involved in cell adhesion and cellular response to vitamin K. Localizes to the collagen-containing extracellular matrix and trans-Golgi network. Biomarker of abdominal aortic aneurysm; chronic kidney disease; congestive heart failure; and degenerative disc disease.
Type:
protein-coding
RefSeq Status:
REVIEWED
Also known as:
MGC119510; MGC119511; OSF-2; OSF2; osteoblast specific factor 2 (fasciclin I-like); osteoblast-specific factor 2; PDLPOSTN; periodontal ligament-specific periostin; periostin isoform thy2; periostin isoform thy4; periostin isoform thy6; periostin isoform thy8; periostin, osteoblast specific factor; PN; RP11-412K4.1
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Mus musculus (house mouse):
Postn (periostin, osteoblast specific factor) HGNC
EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):
Postn (periostin) HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Chinchilla lanigera (long-tailed chinchilla):
Postn (periostin) NCBI
Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):
POSTN (periostin) NCBI
Ortholog
Canis lupus familiaris (dog):
POSTN (periostin) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Postn (periostin) NCBI
Ortholog
Sus scrofa (pig):
POSTN (periostin) HGNC
EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Postn (periostin)
Alliance
DIOPT (Ensembl Compara, HGNC, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER)
Mus musculus (house mouse):
Postn (periostin, osteoblast specific factor)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Danio rerio (zebrafish):
postna (periostin, osteoblast specific factor a)
Alliance
DIOPT (Ensembl Compara, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, TreeFam, ZFIN)
Danio rerio (zebrafish):
postnb (periostin, osteoblast specific factor b)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam, ZFIN)
Caenorhabditis elegans (roundworm):
F26E4.7
Alliance
DIOPT (Ensembl Compara, PANTHER, PhylomeDB, Roundup, TreeFam)
Drosophila melanogaster (fruit fly):
Fas1
Alliance
DIOPT (Ensembl Compara, OrthoFinder, PANTHER, Roundup, TreeFam)
Drosophila melanogaster (fruit fly):
mfas
Alliance
DIOPT (Ensembl Compara, InParanoid, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Drosophila melanogaster (fruit fly):
CG43333
Alliance
DIOPT (Ensembl Compara, PANTHER, TreeFam)
Allele / Splice:
See ClinVar data
Latest Assembly:
GRCh38 - Human Genome Assembly GRCh38
Position:
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 13 37,562,582 - 37,598,844 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh37 13 38,136,719 - 38,172,981 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 13 37,034,779 - 37,070,874 (-) NCBI NCBI36 hg18 NCBI36 Build 34 13 37,034,778 - 37,070,874 NCBI Celera 13 19,190,321 - 19,226,587 (-) NCBI Cytogenetic Map 13 q13.3 NCBI HuRef 13 18,936,182 - 18,972,459 (-) NCBI HuRef CHM1_1 13 38,104,259 - 38,140,559 (-) NCBI CHM1_1
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - CTD
Aspirin-Induced Asthma EXP 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:18391768 Bronchopulmonary Dysplasia EXP 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:22363622 Colorectal Neoplasms EXP 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:15731169 drug allergy EXP 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:18391768 Duchenne muscular dystrophy EXP 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:21641384
Imported Annotations - MGI
aggressive periodontitis ISS RGD:1313224 13592920 OMIM:170650 , OMIM:608526MouseDO bone structure disease ISS RGD:1313224 13592920 MouseDO
(-)-anisomycin increases expression ISO RGD:1305285 6480464 Anisomycin results in increased expression of POSTN mRNA CTD PMID:15121739 1,1-dichloroethene increases expression ISO RGD:1313224 6480464 vinylidene chloride results in increased expression of POSTN mRNA CTD PMID:26682919 1-naphthyl isothiocyanate increases expression ISO RGD:1305285 6480464 1-Naphthylisothiocyanate results in increased expression of POSTN mRNA CTD PMID:30723492 17alpha-ethynylestradiol affects expression ISO RGD:1313224 6480464 Ethinyl Estradiol affects the expression of POSTN mRNA CTD PMID:17555576 17alpha-ethynylestradiol decreases expression ISO RGD:1305285 6480464 Ethinyl Estradiol results in decreased expression of POSTN mRNA CTD PMID:12075121 more ... 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of POSTN mRNA CTD PMID:21795739 17beta-hydroxy-5alpha-androstan-3-one decreases expression ISO RGD:1313224 6480464 Dihydrotestosterone results in decreased expression of POSTN mRNA CTD PMID:17023530 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1313224 6480464 Tetrachlorodibenzodioxin inhibits the reaction [EGF protein results in increased expression of POSTN mRNA] CTD PMID:15667827 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1313224 6480464 Tetrachlorodibenzodioxin results in increased expression of POSTN mRNA CTD PMID:21889950 3-methylcholanthrene decreases expression ISO RGD:1313224 6480464 Methylcholanthrene results in decreased expression of POSTN mRNA CTD PMID:20713471 4,4'-diaminodiphenylmethane increases expression ISO RGD:1305285 6480464 4, 4'-diaminodiphenylmethane results in increased expression of POSTN mRNA CTD PMID:30723492 4,4'-sulfonyldiphenol affects expression ISO RGD:1313224 6480464 bis(4-hydroxyphenyl)sulfone affects the expression of POSTN mRNA CTD PMID:30951980 4,4'-sulfonyldiphenol multiple interactions ISO RGD:1313224 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Tretinoin] results in decreased expression of POSTN mRNA CTD PMID:30951980 4-hydroxyphenyl retinamide increases expression ISO RGD:1313224 6480464 Fenretinide results in increased expression of POSTN mRNA CTD PMID:28973697 5-fluorouracil decreases response to substance EXP 6480464 POSTN protein results in decreased susceptibility to Fluorouracil CTD PMID:15731169 6-propyl-2-thiouracil increases expression ISO RGD:1305285 6480464 Propylthiouracil results in increased expression of POSTN mRNA CTD PMID:24780913 acrylamide decreases expression ISO RGD:1305285 6480464 Acrylamide results in decreased expression of POSTN mRNA CTD PMID:28959563 aflatoxin B1 affects expression EXP 6480464 Aflatoxin B1 affects the expression of POSTN protein CTD PMID:20106945 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of POSTN mRNA CTD PMID:22100608 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of POSTN mRNA CTD PMID:21934132 all-trans-retinoic acid multiple interactions ISO RGD:1313224 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Tretinoin] results in decreased expression of POSTN mRNA more ... CTD PMID:30951980 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of POSTN mRNA CTD PMID:26705709 benzo[a]pyrene decreases expression ISO RGD:1313224 6480464 Benzo(a)pyrene results in decreased expression of POSTN mRNA CTD PMID:20713471 benzo[a]pyrene increases expression ISO RGD:1313224 6480464 Benzo(a)pyrene results in increased expression of POSTN mRNA CTD PMID:21964900 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of POSTN mRNA CTD PMID:22316170 benzo[b]fluoranthene increases expression ISO RGD:1313224 6480464 benzo(b)fluoranthene results in increased expression of POSTN mRNA CTD PMID:26377693 bisphenol A decreases expression ISO RGD:1305285 6480464 bisphenol A results in decreased expression of POSTN mRNA CTD PMID:12075121 , PMID:25181051 bisphenol A increases expression ISO RGD:1313224 6480464 bisphenol A results in increased expression of POSTN mRNA CTD PMID:30951980 bisphenol A multiple interactions ISO RGD:1313224 6480464 [bisphenol A co-treated with Tretinoin] results in decreased expression of POSTN mRNA CTD PMID:30951980 bisphenol A increases expression ISO RGD:1305285 6480464 bisphenol A results in increased expression of POSTN mRNA CTD PMID:29097150 bisphenol F multiple interactions ISO RGD:1313224 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of POSTN mRNA CTD PMID:30951980 bisphenol F increases expression ISO RGD:1313224 6480464 bisphenol F results in increased expression of POSTN mRNA CTD PMID:30951980 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of POSTN mRNA CTD PMID:29741670 cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of POSTN mRNA CTD PMID:29741670 calcium dichloride decreases expression EXP 6480464 Calcium Chloride results in decreased expression of POSTN protein CTD PMID:25824407 choline multiple interactions ISO RGD:1313224 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of POSTN mRNA CTD PMID:20938992 cisplatin decreases response to substance EXP 6480464 POSTN mRNA results in decreased susceptibility to Cisplatin CTD PMID:25199881 cobalt dichloride decreases expression ISO RGD:1305285 6480464 cobaltous chloride results in decreased expression of POSTN mRNA CTD PMID:24386269 copper atom multiple interactions ISO RGD:1313224 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of POSTN mRNA CTD PMID:15467011 copper atom increases expression ISO RGD:1305285 6480464 Copper results in increased expression of POSTN mRNA CTD PMID:30556269 copper atom multiple interactions EXP 6480464 [Disulfiram binds to Copper] which results in increased expression of POSTN mRNA CTD PMID:24690739 copper(0) multiple interactions ISO RGD:1313224 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of POSTN mRNA CTD PMID:15467011 copper(0) increases expression ISO RGD:1305285 6480464 Copper results in increased expression of POSTN mRNA CTD PMID:30556269 copper(0) multiple interactions EXP 6480464 [Disulfiram binds to Copper] which results in increased expression of POSTN mRNA CTD PMID:24690739 curcumin increases expression EXP 6480464 Curcumin results in increased expression of POSTN mRNA CTD PMID:21594647 cyclophosphamide decreases expression ISO RGD:1313224 6480464 Cyclophosphamide results in decreased expression of POSTN mRNA CTD PMID:15331540 cytarabine decreases expression EXP 6480464 Cytarabine results in decreased expression of POSTN mRNA CTD PMID:21198554 decabromodiphenyl ether increases expression ISO RGD:1305285 6480464 decabromobiphenyl ether results in increased expression of POSTN mRNA CTD PMID:23914054 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of POSTN mRNA CTD PMID:25047013 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of POSTN mRNA CTD PMID:26705709 dibutyl phthalate increases expression ISO RGD:1305285 6480464 Dibutyl Phthalate results in increased expression of POSTN mRNA CTD PMID:21266533 dioxygen increases expression ISO RGD:1313224 6480464 Oxygen results in increased expression of POSTN mRNA, Oxygen results in increased expression of POSTN protein CTD PMID:22363622 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of POSTN protein CTD PMID:23728938 dioxygen multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of POSTN protein] more ... CTD PMID:23728938 dioxygen decreases response to substance ISO RGD:1313224 6480464 POSTN gene mutant form results in decreased susceptibility to Oxygen CTD PMID:22363622 dioxygen multiple interactions ISO RGD:1313224 6480464 [POSTN gene mutant form results in decreased susceptibility to Oxygen] which results in decreased expression of ACTA2 mRNA more ... CTD PMID:22363622 disulfiram multiple interactions EXP 6480464 [Disulfiram binds to Copper] which results in increased expression of POSTN mRNA CTD PMID:24690739 diuron decreases expression ISO RGD:1305285 6480464 Diuron results in decreased expression of POSTN mRNA CTD PMID:25152437 dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin multiple interactions ISO RGD:1313224 6480464 DMD protein affects the reaction [Doxorubicin results in decreased expression of POSTN mRNA] CTD PMID:17888722 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of POSTN mRNA CTD PMID:29803840 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of POSTN mRNA CTD PMID:28940058 doxorubicin decreases response to substance EXP 6480464 POSTN mRNA results in decreased susceptibility to Doxorubicin CTD PMID:25199881 doxorubicin multiple interactions ISO RGD:1305285 6480464 Razoxane inhibits the reaction [Doxorubicin results in increased expression of POSTN mRNA] CTD PMID:19915844 doxorubicin increases expression ISO RGD:1305285 6480464 Doxorubicin results in increased expression of POSTN mRNA CTD PMID:19915844 doxorubicin decreases expression ISO RGD:1313224 6480464 Doxorubicin results in decreased expression of POSTN mRNA CTD PMID:17888722 elemental selenium decreases expression EXP 6480464 Selenium results in decreased expression of POSTN mRNA CTD PMID:19244175 entinostat increases expression EXP 6480464 entinostat results in increased expression of POSTN mRNA CTD PMID:26272509 entinostat multiple interactions EXP 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POSTN mRNA CTD PMID:27188386 ethanol multiple interactions ISO RGD:1313224 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of POSTN mRNA CTD PMID:30517762 etoposide increases expression EXP 6480464 Etoposide results in increased expression of POSTN mRNA CTD PMID:29397400 fluorescein 5-isothiocyanate affects binding EXP 6480464 Fluorescein-5-isothiocyanate binds to POSTN protein CTD PMID:27129696 folic acid multiple interactions ISO RGD:1313224 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of POSTN mRNA CTD PMID:20938992 furan increases expression ISO RGD:1305285 6480464 furan results in increased expression of POSTN mRNA CTD PMID:27387713 gamma-aminobutyric acid affects expression ISO RGD:1305285 6480464 gamma-Aminobutyric Acid affects the expression of POSTN mRNA CTD PMID:24098073 gamma-Oryzanol (TN) affects expression ISO RGD:1305285 6480464 gamma-oryzanol affects the expression of POSTN mRNA CTD PMID:24098073 genistein decreases expression ISO RGD:1305285 6480464 Genistein results in decreased expression of POSTN mRNA CTD PMID:12075121 isoprenaline increases expression ISO RGD:1313224 6480464 Isoproterenol results in increased expression of POSTN mRNA CTD PMID:20003209 L-methionine multiple interactions ISO RGD:1313224 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of POSTN mRNA CTD PMID:20938992 lead(0) affects splicing EXP 6480464 Lead affects the splicing of POSTN mRNA CTD PMID:28903495 lead(2+) affects splicing EXP 6480464 Lead affects the splicing of POSTN mRNA CTD PMID:28903495 lipopolysaccharide increases expression ISO RGD:1313224 6480464 Lipopolysaccharides results in increased expression of POSTN mRNA CTD PMID:23585870 losartan multiple interactions ISO RGD:1305285 6480464 Losartan inhibits the reaction [AGT protein results in increased expression of POSTN mRNA] CTD PMID:15121739 losartan decreases expression ISO RGD:1313224 6480464 Losartan results in decreased expression of POSTN mRNA CTD PMID:21641384 LY294002 multiple interactions ISO RGD:1305285 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [AGT protein results in increased expression of POSTN mRNA] more ... CTD PMID:15121739 , PMID:16325820 mercury dibromide multiple interactions EXP 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POSTN mRNA CTD PMID:27188386 methotrexate decreases response to substance EXP 6480464 POSTN mRNA results in decreased susceptibility to Methotrexate CTD PMID:25199881 milrinone increases expression ISO RGD:1305285 6480464 Milrinone results in increased expression of POSTN mRNA CTD PMID:22936366 monocrotaline increases expression ISO RGD:1305285 6480464 Monocrotaline results in increased expression of POSTN protein CTD PMID:24947524 N-methyl-N'-nitro-N-nitrosoguanidine decreases expression ISO RGD:1305285 6480464 Methylnitronitrosoguanidine results in decreased expression of POSTN mRNA CTD PMID:15120970 nickel atom decreases expression EXP 6480464 Nickel results in decreased expression of POSTN mRNA CTD PMID:24768652 , PMID:25583101 nickel sulfate increases expression EXP 6480464 nickel sulfate results in increased expression of POSTN mRNA CTD PMID:22714537 ochratoxin A increases expression ISO RGD:1305285 6480464 ochratoxin A results in increased expression of POSTN mRNA CTD PMID:19717638 oxaliplatin multiple interactions ISO RGD:1305285 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of POSTN mRNA CTD PMID:25729387 paclitaxel decreases response to substance EXP 6480464 POSTN mRNA results in decreased susceptibility to Paclitaxel CTD PMID:25199881 paclitaxel increases expression EXP 6480464 Paclitaxel results in increased expression of POSTN mRNA CTD PMID:19682730 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of POSTN mRNA CTD PMID:21420995 , PMID:29067470 paricalcitol multiple interactions EXP 6480464 [Phosphorus co-treated with paricalcitol] results in decreased expression of POSTN mRNA CTD PMID:17715259 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of POSTN mRNA CTD PMID:27153767 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of POSTN mRNA CTD PMID:19084549 phenobarbital affects expression ISO RGD:1313224 6480464 Phenobarbital affects the expression of POSTN mRNA CTD PMID:19136022 , PMID:23091169 phenylmercury acetate increases expression EXP 6480464 Phenylmercuric Acetate results in increased expression of POSTN mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions EXP 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POSTN mRNA CTD PMID:27188386 phosphorus atom multiple interactions EXP 6480464 [Phosphorus co-treated with paricalcitol] results in decreased expression of POSTN mRNA CTD PMID:17715259 phosphorus(.) multiple interactions EXP 6480464 [Phosphorus co-treated with paricalcitol] results in decreased expression of POSTN mRNA CTD PMID:17715259 pirinixic acid affects expression ISO RGD:1313224 6480464 pirinixic acid affects the expression of POSTN mRNA CTD PMID:19136022 pirinixic acid increases expression ISO RGD:1313224 6480464 pirinixic acid results in increased expression of POSTN mRNA CTD PMID:23811191 potassium chromate decreases expression EXP 6480464 potassium chromate(VI) results in decreased expression of POSTN mRNA CTD PMID:22714537 razoxane multiple interactions ISO RGD:1305285 6480464 Razoxane inhibits the reaction [Doxorubicin results in increased expression of POSTN mRNA] CTD PMID:19915844 rofecoxib affects expression EXP 6480464 rofecoxib affects the expression of POSTN mRNA CTD PMID:17070997 rotenone decreases expression ISO RGD:1305285 6480464 Rotenone results in decreased expression of POSTN mRNA CTD PMID:28374803 SB 203580 multiple interactions ISO RGD:1305285 6480464 SB 203580 inhibits the reaction [AGT protein results in increased expression of POSTN mRNA], SB 203580 inhibits the reaction [FGF1 protein results in increased expression of POSTN mRNA] CTD PMID:15121739 , PMID:17485602 SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 selenium atom decreases expression EXP 6480464 Selenium results in decreased expression of POSTN mRNA CTD PMID:19244175 silicon dioxide decreases expression ISO RGD:1305285 6480464 Silicon Dioxide results in decreased expression of POSTN mRNA CTD PMID:22431001 silver atom decreases expression ISO RGD:1313224 6480464 Silver results in decreased expression of POSTN mRNA CTD PMID:27131904 silver(0) decreases expression ISO RGD:1313224 6480464 Silver results in decreased expression of POSTN mRNA CTD PMID:27131904 sirolimus multiple interactions ISO RGD:1305285 6480464 Sirolimus inhibits the reaction [FGF1 protein results in increased expression of POSTN mRNA] CTD PMID:15121739 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of POSTN mRNA CTD PMID:22714537 sodium arsenite decreases expression ISO RGD:1313224 6480464 sodium arsenite results in decreased expression of POSTN mRNA CTD PMID:30130555 tamoxifen affects expression ISO RGD:1313224 6480464 Tamoxifen affects the expression of POSTN mRNA CTD PMID:17555576 tetrachloromethane increases expression ISO RGD:1313224 6480464 Carbon Tetrachloride results in increased expression of POSTN mRNA CTD PMID:27339419 , PMID:29987408 tetrachloromethane multiple interactions ISO RGD:1313224 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of POSTN mRNA CTD PMID:30517762 topotecan multiple interactions ISO RGD:1305285 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of POSTN mRNA CTD PMID:25729387 topotecan decreases response to substance EXP 6480464 POSTN mRNA results in decreased susceptibility to Topotecan CTD PMID:25199881 trichostatin A increases expression EXP 6480464 trichostatin A results in increased expression of POSTN mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions EXP 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POSTN mRNA CTD PMID:27188386 triclosan increases expression EXP 6480464 Triclosan results in increased expression of POSTN mRNA CTD PMID:30510588 valproic acid decreases methylation EXP 6480464 Valproic Acid results in decreased methylation of POSTN gene CTD PMID:29154799 valproic acid multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POSTN mRNA CTD PMID:27188386 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of POSTN mRNA CTD PMID:23179753 more ... valproic acid increases expression ISO RGD:1313224 6480464 Valproic Acid results in increased expression of POSTN mRNA CTD PMID:24896083 valsartan multiple interactions ISO RGD:1305285 6480464 Valsartan inhibits the reaction [AGT protein results in increased expression of POSTN mRNA] CTD PMID:17485602 vinclozolin affects expression ISO RGD:1305285 6480464 vinclozolin affects the expression of POSTN mRNA CTD PMID:19015723 vincristine decreases response to substance EXP 6480464 POSTN mRNA results in decreased susceptibility to Vincristine CTD PMID:25199881 wortmannin multiple interactions ISO RGD:1305285 6480464 wortmannin inhibits the reaction [AGT protein results in increased expression of POSTN mRNA], wortmannin inhibits the reaction [FGF1 protein results in increased expression of POSTN mRNA] CTD PMID:15121739
Biological Process bone regeneration IEA UniProtKB:D3ZAF5 , ensembl:ENSRNOP000000174532290271 Ensembl GO_REF:0000107 cell adhesion IDA 2290271 (PMID:12235007) UniProtKB PMID:12235007 cell adhesion IBA MGI:MGI:1926321 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 cellular response to fibroblast growth factor stimulus IEA UniProtKB:D3ZAF5 , ensembl:ENSRNOP000000174532290271 Ensembl GO_REF:0000107 cellular response to transforming growth factor beta stimulus IEA UniProtKB:D3ZAF5 , ensembl:ENSRNOP000000174532290271 Ensembl GO_REF:0000107 cellular response to tumor necrosis factor IEA UniProtKB:D3ZAF5 , ensembl:ENSRNOP000000174532290271 Ensembl GO_REF:0000107 cellular response to vitamin K IDA 2290271 (PMID:18450759) UniProtKB PMID:18450759 extracellular matrix organization IBA MGI:MGI:1926321 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 negative regulation of cell-matrix adhesion IEA UniProtKB:D3ZAF5 , ensembl:ENSRNOP000000174532290271 Ensembl GO_REF:0000107 negative regulation of substrate adhesion-dependent cell spreading IEA UniProtKB:D3ZAF5 , ensembl:ENSRNOP000000174532290271 Ensembl GO_REF:0000107 neuron projection extension IEA UniProtKB:D3ZAF5 , ensembl:ENSRNOP000000174532290271 Ensembl GO_REF:0000107 positive regulation of chemokine (C-C motif) ligand 2 secretion IEA UniProtKB:D3ZAF5 , ensembl:ENSRNOP000000174532290271 Ensembl GO_REF:0000107 positive regulation of smooth muscle cell migration IEA UniProtKB:D3ZAF5 , ensembl:ENSRNOP000000174532290271 Ensembl GO_REF:0000107 regulation of Notch signaling pathway IEA UniProtKB:Q62009 , ensembl:ENSMUSP000000727732290271 Ensembl GO_REF:0000107 regulation of systemic arterial blood pressure IEA UniProtKB:D3ZAF5 , ensembl:ENSRNOP000000174532290271 Ensembl GO_REF:0000107 response to estradiol IEA UniProtKB:D3ZAF5 , ensembl:ENSRNOP000000174532290271 Ensembl GO_REF:0000107 response to hypoxia IEA UniProtKB:D3ZAF5 , ensembl:ENSRNOP000000174532290271 Ensembl GO_REF:0000107 response to mechanical stimulus IEA UniProtKB:D3ZAF5 , ensembl:ENSRNOP000000174532290271 Ensembl GO_REF:0000107 response to muscle activity IEA UniProtKB:D3ZAF5 , ensembl:ENSRNOP000000174532290271 Ensembl GO_REF:0000107 Cellular Component collagen-containing extracellular matrix IDA 2290271 (PMID:18450759) UniProt PMID:18450759 collagen-containing extracellular matrix HDA 2290271 (PMID:25037231), (PMID:27068509), (PMID:27559042), (PMID:28327460), (PMID:28675934) BHF-UCL PMID:25037231 more ... collagen-containing extracellular matrix colocalizes_with HDA 2290271 (PMID:20551380) BHF-UCL PMID:20551380 extracellular matrix IBA MGI:MGI:1926321 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 extracellular matrix ISS UniProtKB:Q62009 2290271 UniProtKB GO_REF:0000024 extracellular space IBA MGI:MGI:99959 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 neuromuscular junction IEA UniProtKB:D3ZAF5 , ensembl:ENSRNOP000000174532290271 Ensembl GO_REF:0000107 trans-Golgi network IDA 2290271 (PMID:19478074) BHF-UCL PMID:19478074 Molecular Function cell adhesion molecule binding IBA FB:FBgn0285925 , PANTHER:PTN000855676 2290271 (PMID:21873635) GO_Central PMID:21873635 extracellular matrix structural constituent RCA 2290271 (PMID:20551380), (PMID:25037231), (PMID:27068509), (PMID:27559042), (PMID:28327460), (PMID:28675934) BHF-UCL PMID:20551380 more ... heparin binding ISS UniProtKB:Q62009 2290271 UniProtKB GO_REF:0000024 metal ion binding IDA 2290271 (PMID:18450759) UniProtKB PMID:18450759 protein binding IPI UniProtKB:Q15582 2290271 (PMID:19478074) BHF-UCL PMID:19478074
Gene-Chemical Interaction Annotations
