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Gene: WFDC3 (WAP four-disulfide core domain 3) Homo sapiens
Symbol: WFDC3
Name: WAP four-disulfide core domain 3
Description: Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to localize to the extracellular region.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dJ447F3.3; protease inhibitor WAP14; putative protease inhibitor WAP14; WAP four-disulfide core domain protein 3; WAP14; whey acidic protein 14
Mus musculus (house mouse) : Wfdc3 (WAP four-disulfide core domain 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Wfdc3 (WAP four-disulfide core domain 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wfdc3 (WAP four-disulfide core domain 3)
Pan paniscus (bonobo/pygmy chimpanzee) : WFDC3 (WAP four-disulfide core domain 3)
Canis lupus familiaris (dog) : WFDC3 (WAP four-disulfide core domain 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wfdc3 (WAP four-disulfide core domain 3)
Sus scrofa (pig) : WFDC3 (WAP four-disulfide core domain 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382045,708,860 - 45,791,883 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372044,402,847 - 44,420,547 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362043,836,254 - 43,853,954 (-)NCBINCBI36hg18NCBI36
Build 342043,836,253 - 43,853,954NCBI
Celera2041,113,350 - 41,131,041 (-)NCBI
Cytogenetic Map20q13.12NCBI
HuRef2041,144,647 - 41,162,351 (-)NCBIHuRef
CHM1_12044,305,556 - 44,323,245 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on WFDC3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313240
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.