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Gene: Mars1 (methionine-tRNA synthetase 1) Mus musculus
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Symbol: Mars1
Name: methionine-tRNA synthetase 1
Description: Exhibits methionine-tRNA ligase activity. Involved in methionyl-tRNA aminoacylation. Localizes to aminoacyl-tRNA synthetase multienzyme complex. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2U. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human MARS1 (methionyl-tRNA synthetase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Mars; methionine tRNA ligase; methionine--tRNA ligase; methionine--tRNA ligase, cytoplasmic; methionine-tRNA synthetase; methionyl-tRNA synthetase, cytoplasmic; MetRS; MGC90747; MTRNS
Orthologs:
Homo sapiens (human) : MARS1 (methionyl-tRNA synthetase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mars1 (methionyl-tRNA synthetase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mars1 (methionyl-tRNA synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MARS1 (methionyl-tRNA synthetase 1)
Canis lupus familiaris (dog) : MARS1 (methionyl-tRNA synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mars1 (methionyl-tRNA synthetase 1)
Sus scrofa (pig) : MARS1 (methionyl-tRNA synthetase 1)
Chlorocebus sabaeus (African green monkey) : MARS1 (methionyl-tRNA synthetase 1)
Heterocephalus glaber (naked mole-rat) : Mars1 (methionyl-tRNA synthetase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl10127,296,221 - 127,311,786 (-)EnsemblGRCm38mm10GRCm38
GRCm3810127,296,221 - 127,311,786 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710126,733,277 - 126,748,842 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610126,699,175 - 126,714,588 (-)NCBImm8
Celera10129,688,532 - 129,704,394 (-)NCBICelera
Cytogenetic Map10D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Mars1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313281
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.