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Gene: Hic2 (hypermethylated in cancer 2) Mus musculus
Symbol: Hic2
Name: hypermethylated in cancer 2
Description: Predicted to have protein C-terminus binding activity. Predicted to be involved in cellular response to DNA damage stimulus. Predicted to localize to nucleoplasm. Is expressed in female reproductive system and urinary system. Orthologous to human HIC2 (HIC ZBTB transcriptional repressor 2); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 5-aza-2'-deoxycytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA409108; hic-2; HRG22; hypermethylated in cancer 2 protein; mKIAA1020
Homo sapiens (human) : HIC2 (HIC ZBTB transcriptional repressor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hic2 (HIC ZBTB transcriptional repressor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hic2 (HIC ZBTB transcriptional repressor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HIC2 (HIC ZBTB transcriptional repressor 2)
Canis lupus familiaris (dog) : HIC2 (HIC ZBTB transcriptional repressor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hic2 (HIC ZBTB transcriptional repressor 2)
Sus scrofa (pig) : HIC2 (HIC ZBTB transcriptional repressor 2)
Chlorocebus sabaeus (African green monkey) : HIC2 (HIC ZBTB transcriptional repressor 2)
Heterocephalus glaber (naked mole-rat) : Hic2 (HIC ZBTB transcriptional repressor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1617,233,572 - 17,263,430 (+)EnsemblGRCm38mm10GRCm38
GRCm381617,233,587 - 17,263,430 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371617,233,680 - 17,263,523 (+)NCBIGRCm37mm9NCBIm37
MGSCv361617,147,150 - 17,176,993 (+)NCBImm8
Celera1617,806,402 - 17,836,239 (+)NCBICelera
Cytogenetic Map16A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hic2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313308
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.