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Gene: UBE2C (ubiquitin conjugating enzyme E2 C) Homo sapiens
Symbol: UBE2C
Name: ubiquitin conjugating enzyme E2 C
Description: Exhibits ubiquitin conjugating enzyme activity and ubiquitin-like protein ligase binding activity. Involved in several processes, including anaphase-promoting complex-dependent catabolic process; free ubiquitin chain polymerization; and protein polyubiquitination. Localizes to the anaphase-promoting complex; cytosol; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: (E3-independent) E2 ubiquitin-conjugating enzyme C; cyclin-selective ubiquitin carrier protein; dJ447F3.2; E2 ubiquitin-conjugating enzyme C; mitotic-specific ubiquitin-conjugating enzyme; UBCH10; ubiquitin carrier protein C; ubiquitin carrier protein E2-C; ubiquitin conjugating enzyme E2C; ubiquitin-conjugating enzyme E2 C; ubiquitin-conjugating enzyme E2C; ubiquitin-protein ligase C
Mus musculus (house mouse) : Ube2c (ubiquitin-conjugating enzyme E2C)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ube2c (ubiquitin-conjugating enzyme E2C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ube2c (ubiquitin conjugating enzyme E2 C)
Pan paniscus (bonobo/pygmy chimpanzee) : UBE2C (ubiquitin conjugating enzyme E2 C)
Canis lupus familiaris (dog) : UBE2C (ubiquitin conjugating enzyme E2 C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ube2c (ubiquitin conjugating enzyme E2 C)
Sus scrofa (pig) : UBE2C (ubiquitin conjugating enzyme E2 C)
more info ...
Related Pseudogenes: UBE2CP1   UBE2CP2   UBE2CP3   UBE2CP4   UBE2CP5  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382045,812,576 - 45,816,957 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372044,441,255 - 44,445,596 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362043,874,662 - 43,879,003 (+)NCBINCBI36hg18NCBI36
Build 342043,874,661 - 43,879,001NCBI
Celera2041,151,754 - 41,156,092 (+)NCBI
Cytogenetic Map20q13.12NCBI
HuRef2041,183,027 - 41,187,357 (+)NCBIHuRef
CHM1_12044,344,357 - 44,348,735 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on UBE2C
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313378
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.