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Gene: Kdm5a (lysine (K)-specific demethylase 5A) Mus musculus
Symbol: Kdm5a
Name: lysine (K)-specific demethylase 5A
CRRD ID: 1313453
Description: Exhibits chromatin DNA binding activity and transcription coactivator activity. Involved in circadian regulation of gene expression; histone H3-K4 demethylation; and negative regulation of nitrogen compound metabolic process. Localizes to nucleus and protein-DNA complex. Is expressed in several structures, including 1st branchial arch; early conceptus; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in ankylosing spondylitis. Orthologous to human KDM5A (lysine demethylase 5A); PARTICIPATES IN histone modification pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: [histone H3]-trimethyl-L-lysine(4) demethylase 5A; AA409370; C76986; histone demethylase JARID1A; Jar; Jarid1a; jumonji, AT rich interactive domain 1A (Rbp2 like); jumonji/ARID domain-containing protein 1A; lysine-specific demethylase 5A; MGC11659; RB; Rbb; RBBP-2; Rbbp2; RBP2; retinoblastoma binding protein 2; retinoblastoma-binding protein 2
Homo sapiens (human) : KDM5A (lysine demethylase 5A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm5a (lysine demethylase 5A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm5a (lysine demethylase 5A)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM5A (lysine demethylase 5A)
Canis lupus familiaris (dog) : KDM5A (lysine demethylase 5A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm5a (lysine demethylase 5A)
Sus scrofa (pig) : KDM5A (lysine demethylase 5A)
Chlorocebus sabaeus (African green monkey) : KDM5A (lysine demethylase 5A)
Heterocephalus glaber (naked mole-rat) : Kdm5a (lysine demethylase 5A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm396120,341,060 - 120,421,535 (+)NCBI
GRCm386120,364,099 - 120,444,574 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6120,364,124 - 120,444,574 (+)EnsemblGRCm38mm10GRCm38
MGSCv376120,314,117 - 120,394,592 (+)NCBIGRCm37mm9NCBIm37
MGSCv366120,327,955 - 120,405,330 (+)NCBImm8
Celera6122,200,858 - 122,281,399 (+)NCBICelera
Cytogenetic Map6F1NCBI
cM Map656.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kdm5a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313453
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.