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Gene: Kdm5a (lysine (K)-specific demethylase 5A) Mus musculus
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Symbol: Kdm5a
Name: lysine (K)-specific demethylase 5A
CRRD ID: 1313453
Description: Exhibits chromatin DNA binding activity and transcription coactivator activity. Involved in circadian regulation of gene expression; histone H3-K4 demethylation; and negative regulation of nitrogen compound metabolic process. Localizes to nucleus and protein-DNA complex. Is expressed in several structures, including 1st branchial arch; early conceptus; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in ankylosing spondylitis. Orthologous to human KDM5A (lysine demethylase 5A); PARTICIPATES IN histone modification pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: [histone H3]-trimethyl-L-lysine(4) demethylase 5A; AA409370; C76986; histone demethylase JARID1A; Jar; Jarid1a; jumonji, AT rich interactive domain 1A (Rbp2 like); jumonji/ARID domain-containing protein 1A; lysine-specific demethylase 5A; MGC11659; RB; Rbb; RBBP-2; Rbbp2; RBP2; retinoblastoma binding protein 2; retinoblastoma-binding protein 2
Orthologs:
Homo sapiens (human) : KDM5A (lysine demethylase 5A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm5a (lysine demethylase 5A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm5a (lysine demethylase 5A)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM5A (lysine demethylase 5A)
Canis lupus familiaris (dog) : KDM5A (lysine demethylase 5A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm5a (lysine demethylase 5A)
Sus scrofa (pig) : KDM5A (lysine demethylase 5A)
Chlorocebus sabaeus (African green monkey) : KDM5A (lysine demethylase 5A)
Heterocephalus glaber (naked mole-rat) : Kdm5a (lysine demethylase 5A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396120,341,060 - 120,421,535 (+)NCBI
GRCm386120,364,099 - 120,444,574 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6120,364,124 - 120,444,574 (+)EnsemblGRCm38mm10GRCm38
MGSCv376120,314,117 - 120,394,592 (+)NCBIGRCm37mm9NCBIm37
MGSCv366120,327,955 - 120,405,330 (+)NCBImm8
Celera6122,200,858 - 122,281,399 (+)NCBICelera
Cytogenetic Map6F1NCBI
cM Map656.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Kdm5a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313453
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.