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Gene: CDH20 (cadherin 20) Homo sapiens
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Symbol: CDH20
Name: cadherin 20
Description: This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cadherin 20, type 2; cadherin-20; Cdh7; CDH7L3; FLJ37047
Orthologs:
Mus musculus (house mouse) : Cdh20 (cadherin 20)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdh20 (cadherin 20)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdh20 (cadherin 20)
Pan paniscus (bonobo/pygmy chimpanzee) : CDH20 (cadherin 20)
Canis lupus familiaris (dog) : CDH20 (cadherin 20)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdh20 (cadherin 20)
Sus scrofa (pig) : CDH20 (cadherin 20)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381861,333,582 - 61,555,773 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371859,000,815 - 59,237,123 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361857,308,755 - 57,373,345 (+)NCBINCBI36hg18NCBI36
Build 341857,308,754 - 57,373,345NCBI
Celera1855,875,642 - 55,940,232 (+)NCBI
Cytogenetic Map18q21.33NCBI
HuRef1855,867,814 - 55,931,773 (+)NCBIHuRef
CHM1_11858,996,281 - 59,218,613 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CDH20
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313468
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.