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Gene: GPT2 (glutamic--pyruvic transaminase 2) Homo sapiens
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Symbol: GPT2
Name: glutamic--pyruvic transaminase 2
Description: Exhibits L-alanine:2-oxoglutarate aminotransferase activity. Involved in 2-oxoglutarate metabolic process and L-alanine metabolic process. Predicted to localize to the mitochondrial matrix. Implicated in autosomal recessive non-syndromic intellectual disability. Biomarker of liver cancer and non-alcoholic fatty liver disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alanine aminotransferase 2; ALT2; glutamate pyruvate transaminase 2; glutamic pyruvate transaminase (alanine aminotransferase) 2; glutamic pyruvate transaminase 2; glutamic--alanine transaminase 2; glutamic-pyruvate transaminase 2; GPT 2; MRT49
Orthologs:
Mus musculus (house mouse) : Gpt2 (glutamic pyruvate transaminase (alanine aminotransferase) 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gpt2 (glutamic--pyruvic transaminase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpt2 (glutamic--pyruvic transaminase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GPT2 (glutamic--pyruvic transaminase 2)
Canis lupus familiaris (dog) : GPT2 (glutamic--pyruvic transaminase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpt2 (glutamic--pyruvic transaminase 2)
Sus scrofa (pig) : GPT2 (glutamic--pyruvic transaminase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381646,884,362 - 46,931,289 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371646,918,308 - 46,965,201 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361645,475,809 - 45,522,699 (+)NCBINCBI36hg18NCBI36
Build 341645,475,808 - 45,522,699NCBI
Celera1631,426,465 - 31,473,333 (+)NCBI
Cytogenetic Map16q11.2NCBI
HuRef1632,808,713 - 32,855,581 (+)NCBIHuRef
CHM1_11648,325,386 - 48,372,277 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on GPT2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313502
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.