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Gene: Atf6 (activating transcription factor 6) Mus musculus
Symbol: Atf6
Name: activating transcription factor 6
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; protein heterodimerization activity; and ubiquitin protein ligase binding activity. Involved in positive regulation of transcription by RNA polymerase II. Localizes to nucleus. Human ortholog(s) of this gene implicated in achromatopsia 7. Is expressed in several structures, including brain; embryo mesenchyme; eye; heart; and long bone. Orthologous to human ATF6 (activating transcription factor 6); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; Alzheimer's disease pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (R)-lipoic acid; 1H-pyrazole; 2,4-dichlorophenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9130025P16Rik; 9630036G24; AA789574; activating transcription factor 6 alpha; ATF6-alpha; Atf6alpha; cAMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 alpha; ESTM49
Homo sapiens (human) : ATF6 (activating transcription factor 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Atf6 (activating transcription factor 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atf6 (activating transcription factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : ATF6 (activating transcription factor 6)
Canis lupus familiaris (dog) : ATF6 (activating transcription factor 6)
Sus scrofa (pig) : ATF6 (activating transcription factor 6)
Chlorocebus sabaeus (African green monkey) : ATF6 (activating transcription factor 6)
Heterocephalus glaber (naked mole-rat) : Atf6 (activating transcription factor 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1170,704,674 - 170,867,771 (-)EnsemblGRCm38mm10GRCm38
GRCm381170,704,457 - 170,868,585 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371172,634,588 - 172,797,902 (-)NCBIGRCm37mm9NCBIm37
MGSCv361172,541,132 - 172,710,564 (-)NCBImm8
Celera1173,146,825 - 173,324,073 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map176.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Atf6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313518
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-05-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.