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Gene: RNF2 (ring finger protein 2) Homo sapiens
Symbol: RNF2
Name: ring finger protein 2
Description: Exhibits RING-like zinc finger domain binding activity; chromatin binding activity; and zinc ion binding activity. Contributes to ubiquitin-protein transferase activity. Involved in histone H2A monoubiquitination and negative regulation of DNA-binding transcription factor activity. Localizes to the MLL1 complex; PRC1 complex; and nuclear body. Biomarker of pancreatic ductal carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BAP-1; BAP1; DING; E3 ubiquitin-protein ligase RING2; HIP2-interacting protein 3; HIPI3; huntingtin-interacting protein 2-interacting protein 3; RING finger protein 1B; RING finger protein BAP-1; RING-type E3 ubiquitin transferase RING2; RING1B; RING2
Mus musculus (house mouse) : Rnf2 (ring finger protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rnf2 (ring finger protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rnf2 (ring finger protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RNF2 (ring finger protein 2)
Canis lupus familiaris (dog) : RNF2 (ring finger protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rnf2 (ring finger protein 2)
Sus scrofa (pig) : RNF2 (ring finger protein 2)
Chlorocebus sabaeus (African green monkey) : RNF2 (ring finger protein 2)
Heterocephalus glaber (naked mole-rat) : Rnf2 (ring finger protein 2)
more info ...
Related Pseudogenes: RNF2P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1185,045,526 - 185,102,603 (+)EnsemblGRCh38hg38GRCh38
GRCh381185,045,430 - 185,102,603 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371185,014,482 - 185,071,740 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361183,281,174 - 183,338,363 (+)NCBINCBI36hg18NCBI36
Build 341181,746,207 - 181,803,397NCBI
Celera1158,125,254 - 158,182,437 (+)NCBI
Cytogenetic Map1q25.3NCBI
HuRef1156,249,794 - 156,306,846 (+)NCBIHuRef
CHM1_11186,434,264 - 186,493,430 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on RNF2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313548
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.