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Gene: SEMA6A (semaphorin 6A) Homo sapiens
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Symbol: SEMA6A
Name: semaphorin 6A
Description: Predicted to have chemorepellent activity and semaphorin receptor binding activity. Involved in cellular response to vascular endothelial growth factor stimulus; negative regulation of cell adhesion involved in sprouting angiogenesis; and negative regulation of signal transduction. Predicted to localize to the extracellular space and integral component of plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HT018; KIAA1368; SEMA; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A; sema VIa; SEMA6A-1; SEMA6A1; semaphorin 6A-1; semaphorin VIA; semaphorin-6A; semaphorin-6A-1; SEMAQ; VIA
Orthologs:
Mus musculus (house mouse) : Sema6a (sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sema6a (semaphorin 6A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sema6a (semaphorin 6A)
Pan paniscus (bonobo/pygmy chimpanzee) : SEMA6A (semaphorin 6A)
Canis lupus familiaris (dog) : SEMA6A (semaphorin 6A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sema6a (semaphorin 6A)
Sus scrofa (pig) : SEMA6A (semaphorin 6A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385116,443,555 - 116,574,823 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375115,779,251 - 115,910,551 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365115,807,150 - 115,938,450 (-)NCBINCBI36hg18NCBI36
Build 345115,807,150 - 115,938,398NCBI
Celera5111,728,814 - 111,860,108 (-)NCBI
Cytogenetic Map5q23.1NCBI
HuRef5110,960,448 - 111,091,731 (-)NCBIHuRef
CHM1_15115,211,962 - 115,342,992 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SEMA6A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313551
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.