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Gene: ARL6 (ADP ribosylation factor like GTPase 6) Homo sapiens
Symbol: ARL6
Name: ADP ribosylation factor like GTPase 6
Description: Predicted to have GTP binding activity and phospholipid binding activity. Involved in Wnt signaling pathway; cilium assembly; and protein localization to cilium. Localizes to the cilium. Implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 1; Bardet-Biedl syndrome 3; and retinitis pigmentosa 55.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADP-ribosylation factor like GTPase 6; ADP-ribosylation factor-like 6; ADP-ribosylation factor-like protein 6; bardet-Biedl syndrome 3 protein; BBS3; MGC32934; RP55
Mus musculus (house mouse) : Arl6 (ADP-ribosylation factor-like 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arl6 (ADP-ribosylation factor like GTPase 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arl6 (ADP ribosylation factor like GTPase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : ARL6 (ADP ribosylation factor like GTPase 6)
Canis lupus familiaris (dog) : ARL6 (ADP ribosylation factor like GTPase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arl6 (ADP ribosylation factor like GTPase 6)
Sus scrofa (pig) : ARL6 (ADP ribosylation factor like GTPase 6)
Chlorocebus sabaeus (African green monkey) : ARL6 (ADP ribosylation factor like GTPase 6)
Heterocephalus glaber (naked mole-rat) : Arl6 (ADP ribosylation factor like GTPase 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl397,764,521 - 97,801,229 (+)EnsemblGRCh38hg38GRCh38
GRCh38397,762,581 - 97,812,585 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37397,483,365 - 97,520,086 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36398,966,285 - 99,000,063 (+)NCBINCBI36hg18NCBI36
Build 34398,966,284 - 99,000,061NCBI
Celera395,873,167 - 95,906,953 (+)NCBI
Cytogenetic Map3q11.2NCBI
HuRef394,853,270 - 94,889,996 (+)NCBIHuRef
CHM1_1397,446,398 - 97,483,119 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ARL6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313618
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.