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Gene: MCM2 (minichromosome maintenance complex component 2) Homo sapiens
Symbol: MCM2
Name: minichromosome maintenance complex component 2
Description: Predicted to contribute to 3'-5' DNA helicase activity and single-stranded DNA helicase activity. Involved in DNA replication initiation; apoptotic process; and cochlea development. Localizes to several cellular components, including the MCM complex; chromatin; and microtubule cytoskeleton. Implicated in Alzheimer's disease and autosomal dominant nonsyndromic deafness 70.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BM28; CCNL1; cdc19; CDCL1; cell devision cycle-like 1; cyclin-like 1; D3S3194; DFNA70; DNA replication licensing factor MCM2; KIAA0030; MCM2 minichromosome maintenance deficient 2, mitotin; mcm2 minichromosome maintenance deficient 2, mitotin (s. cerevisiae); MGC10606; minichromosome maintenance deficient 2 (mitotin); minichromosome maintenance protein 2 homolog; MITOTIN; nuclear protein BM28
Mus musculus (house mouse) : Mcm2 (minichromosome maintenance complex component 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mcm2 (minichromosome maintenance complex component 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mcm2 (minichromosome maintenance complex component 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MCM2 (minichromosome maintenance complex component 2)
Canis lupus familiaris (dog) : MCM2 (minichromosome maintenance complex component 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mcm2 (minichromosome maintenance complex component 2)
Sus scrofa (pig) : MCM2 (minichromosome maintenance complex component 2)
Chlorocebus sabaeus (green monkey) : MCM2 (minichromosome maintenance complex component 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl3127,598,410 - 127,622,436 (+)Ensembl
GRCh383127,598,411 - 127,622,436 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373127,317,200 - 127,341,279 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363128,799,943 - 128,823,969 (+)NCBINCBI36hg18NCBI36
Build 343128,799,950 - 128,823,974NCBI
Celera3125,743,735 - 125,767,756 (+)NCBI
Cytogenetic Map3q21.3NCBI
HuRef3124,697,246 - 124,721,320 (+)NCBIHuRef
CHM1_13127,280,516 - 127,304,609 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MCM2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313689
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.