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Gene: EPHB3 (EPH receptor B3) Homo sapiens
Symbol: EPHB3
Name: EPH receptor B3
Description: Exhibits ephrin receptor activity. Involved in several processes, including ephrin receptor signaling pathway; protein autophosphorylation; and substrate adhesion-dependent cell spreading. Localizes to integral component of plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EK2; embryonic kinase 2; EPH-like kinase 2; EPH-like tyrosine kinase 2; EPH-like tyrosine kinase-2; ephrin type-B receptor 3; ETK2; HEK2; human embryo kinase 2; TYRO6; tyrosine-protein kinase TYRO6
Mus musculus (house mouse) : Ephb3 (Eph receptor B3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ephb3 (Eph receptor B3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ephb3 (EPH receptor B3)
Pan paniscus (bonobo/pygmy chimpanzee) : EPHB3 (EPH receptor B3)
Canis lupus familiaris (dog) : EPHB3 (EPH receptor B3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ephb3 (EPH receptor B3)
Sus scrofa (pig) : EPHB3 (EPH receptor B3)
Chlorocebus sabaeus (African green monkey) : EPHB3 (EPH receptor B3)
Heterocephalus glaber (naked mole-rat) : Ephb3 (EPH receptor B3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl3184,561,785 - 184,582,408 (+)EnsemblGRCh38hg38GRCh38
GRCh383184,561,785 - 184,582,408 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373184,279,587 - 184,300,196 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363185,762,281 - 185,782,890 (+)NCBINCBI36hg18NCBI36
Build 343185,762,288 - 185,782,897NCBI
Celera3182,727,556 - 182,748,228 (+)NCBI
Cytogenetic Map3q27.1NCBI
HuRef3181,691,476 - 181,712,092 (+)NCBIHuRef
CHM1_13184,243,646 - 184,264,249 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on EPHB3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313727
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.