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Gene: ADGRB1 (adhesion G protein-coupled receptor B1) Homo sapiens
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Symbol: ADGRB1
Name: adhesion G protein-coupled receptor B1
Description: Exhibits G protein-coupled receptor activity. Involved in several processes, including engulfment of apoptotic cell; negative regulation of endothelial cell migration; and positive regulation of reactive oxygen species biosynthetic process. Localizes to extracellular space; perinuclear region of cytoplasm; and plasma membrane. Implicated in glioblastoma multiforme. Biomarker of astrocytoma (multiple); carcinoma (multiple); gastrointestinal system cancer (multiple); and invasive ductal carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BAI1; brain-specific angiogenesis inhibitor 1; FLJ41988; GDAIF
Orthologs:
Mus musculus (house mouse) : Adgrb1 (adhesion G protein-coupled receptor B1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Adgrb1 (adhesion G protein-coupled receptor B1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adgrb1 (adhesion G protein-coupled receptor B1)
Pan paniscus (bonobo/pygmy chimpanzee) : ADGRB1 (adhesion G protein-coupled receptor B1)
Canis lupus familiaris (dog) : ADGRB1 (adhesion G protein-coupled receptor B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adgrb1 (adhesion G protein-coupled receptor B1)
Sus scrofa (pig) : ADGRB1 (adhesion G protein-coupled receptor B1)
Chlorocebus sabaeus (African green monkey) : ADGRB1 (adhesion G protein-coupled receptor B1)
Heterocephalus glaber (naked mole-rat) : Adgrb1 (adhesion G protein-coupled receptor B1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl8142,449,430 - 142,545,009 (+)EnsemblGRCh38hg38GRCh38
GRCh388142,449,649 - 142,545,009 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh378143,545,377 - 143,626,369 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368143,542,379 - 143,623,370 (+)NCBINCBI36hg18NCBI36
Build 348143,542,378 - 143,623,369NCBI
Celera8139,855,778 - 139,937,685 (+)NCBI
Cytogenetic Map8q24.3ENTREZGENE
HuRef8138,802,096 - 138,882,338 (+)NCBIHuRef
CHM1_18143,585,613 - 143,666,276 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ADGRB1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313737
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.