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Gene: Elovl4 (elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4) Mus musculus
Symbol: Elovl4
Name: elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
Description: Exhibits fatty acid elongase activity. Involved in fatty acid elongation, polyunsaturated fatty acid. Predicted to localize to the endoplasmic reticulum and integral component of endoplasmic reticulum membrane. Used to study Stargardt disease. Human ortholog(s) of this gene implicated in corneal dystrophy and spinocerebellar ataxia type 34. Is expressed in several structures, including central nervous system; eye; genitourinary system; skin; and spleen. Orthologous to human ELOVL4 (ELOVL fatty acid elongase 4); PARTICIPATES IN alpha-linoleic acid metabolic pathway; linoleic acid metabolic pathway; INTERACTS WITH 17beta-estradiol; Benzo[k]fluoranthene; cisplatin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3-keto acyl-CoA synthase Elovl4; elongation of very long chain fatty acids protein 4; ELOVL FA elongase 4; ELOVL fatty acid elongase 4; very long chain 3-ketoacyl-CoA synthase 4; very long chain 3-oxoacyl-CoA synthase 4; very-long-chain 3-oxoacyl-CoA synthase 4
Homo sapiens (human) : ELOVL4 (ELOVL fatty acid elongase 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Elovl4 (ELOVL fatty acid elongase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Elovl4 (ELOVL fatty acid elongase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ELOVL4 (ELOVL fatty acid elongase 4)
Canis lupus familiaris (dog) : ELOVL4 (ELOVL fatty acid elongase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Elovl4 (ELOVL fatty acid elongase 4)
Sus scrofa (pig) : ELOVL4 (ELOVL fatty acid elongase 4)
Chlorocebus sabaeus (African green monkey) : ELOVL4 (ELOVL fatty acid elongase 4)
Heterocephalus glaber (naked mole-rat) : Elovl4 (ELOVL fatty acid elongase 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl983,778,692 - 83,806,277 (-)Ensembl
GRCm38983,778,692 - 83,806,305 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37983,672,299 - 83,699,912 (-)NCBIGRCm37mm9NCBIm37
MGSCv36983,575,410 - 83,602,818 (-)NCBImm8
Celera980,877,487 - 80,906,281 (-)NCBICelera
Cytogenetic Map9 E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Elovl4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313773
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.