Tbx5 (T-box 5) - Chinchilla Research Resource Database
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Gene: Tbx5 (T-box 5) Mus musculus
Analyze
Symbol: Tbx5
Name: T-box 5
CRRD ID: 1313888
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including embryonic forelimb morphogenesis; heart development; and positive regulation of cell population proliferation. Localizes to nucleus and transcription regulator complex. Is expressed in several structures, including embryo mesenchyme; eye; genitourinary system; heart; and vena cava. Used to study Holt-Oram syndrome. Human ortholog(s) of this gene implicated in Holt-Oram syndrome. Orthologous to human TBX5 (T-box transcription factor 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: T-box protein 5; T-box transcription factor TBX5
Orthologs:
Homo sapiens (human) : TBX5 (T-box transcription factor 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tbx5 (T-box transcription factor 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbx5 (T-box transcription factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : TBX5 (T-box transcription factor 5)
Canis lupus familiaris (dog) : TBX5 (T-box transcription factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbx5 (T-box transcription factor 5)
Sus scrofa (pig) : TBX5 (T-box transcription factor 5)
Chlorocebus sabaeus (African green monkey) : TBX5 (T-box transcription factor 5)
Heterocephalus glaber (naked mole-rat) : Tbx5 (T-box transcription factor 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395119,934,581 - 120,023,285 (+)NCBI
GRCm385119,796,514 - 119,885,220 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5119,832,668 - 119,885,219 (+)EnsemblGRCm38mm10GRCm38
MGSCv375120,284,672 - 120,335,227 (+)NCBIGRCm37mm9NCBIm37
MGSCv365120,095,280 - 120,145,092 (+)NCBImm8
Celera5116,903,647 - 116,978,836 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map560.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal abdominal wall morphology  (IAGP)
abnormal atrioventricular bundle conduction  (IAGP)
abnormal atrioventricular bundle morphology  (IAGP)
abnormal atrioventricular node conduction  (IAGP)
abnormal atrioventricular valve morphology  (IAGP)
abnormal cardiovascular system physiology  (IAGP)
abnormal carpal bone morphology  (IAGP)
abnormal digit morphology  (IAGP)
abnormal forelimb bud morphology  (IAGP)
abnormal forelimb morphology  (IAGP)
abnormal heart atrium morphology  (IAGP)
abnormal heart development  (IAGP)
abnormal heart left ventricle morphology  (IAGP)
abnormal heart morphology  (IAGP)
abnormal heart tube morphology  (IAGP)
abnormal heart ventricle morphology  (IAGP)
abnormal impulse conducting system conduction  (IAGP)
abnormal impulse conducting system morphology  (IAGP)
abnormal induced morbidity/mortality  (IAGP)
abnormal left posterior bundle morphology  (IAGP)
abnormal limb development  (IAGP)
abnormal mitral valve morphology  (IAGP)
abnormal phalanx morphology  (IAGP)
abnormal right bundle morphology  (IAGP)
abnormal sinoatrial node conduction  (IAGP)
abnormal sinus arrhythmia  (IAGP)
abnormal tendon morphology  (IAGP)
abnormal thoracic cage morphology  (IAGP)
absent apical ectodermal ridge  (IAGP)
absent atrioventricular cushions  (IAGP)
absent clavicle  (IAGP)
absent forelimb  (IAGP)
absent forelimb buds  (IAGP)
absent scapula  (IAGP)
absent sternum  (IAGP)
atrial septal defect  (IAGP)
atrioventricular block  (IAGP)
atrium hypoplasia  (IAGP)
common atrium  (IAGP)
dilated heart atrium  (IAGP)
embryonic growth arrest  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
enlarged heart  (IAGP)
failure of heart looping  (IAGP)
hydrops fetalis  (IAGP)
irregular heartbeat  (IAGP)
muscular ventricular septal defect  (IAGP)
no abnormal phenotype detected  (IAGP)
ostium primum atrial septal defect  (IAGP)
pericardial effusion  (IAGP)
perimembraneous ventricular septal defect  (IAGP)
perinatal lethality  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
prolonged P wave  (IAGP)
prolonged PQ interval  (IAGP)
prolonged PR interval  (IAGP)
prolonged QRS complex duration  (IAGP)
sinoatrial block  (IAGP)
ventricular premature beat  (IAGP)
ventricular septal defect  (IAGP)
ventricular tachycardia  (IAGP)
References

Additional References at PubMed
PMID:1375456   PMID:7688225   PMID:8798150   PMID:8853987   PMID:8878690   PMID:8954725   PMID:8988164   PMID:9503012   PMID:9916808   PMID:10049363   PMID:10101115   PMID:10349636  
PMID:10373308   PMID:10864469   PMID:10882515   PMID:11042159   PMID:11076746   PMID:11076861   PMID:11217851   PMID:11238910   PMID:11245568   PMID:11431700   PMID:11437453   PMID:11456441  
PMID:11520674   PMID:11555635   PMID:11726608   PMID:11784028   PMID:11830578   PMID:11830579   PMID:11891982   PMID:11923873   PMID:11959834   PMID:12023302   PMID:12074552   PMID:12118102  
PMID:12142027   PMID:12175489   PMID:12223410   PMID:12376111   PMID:12399308   PMID:12466851   PMID:12477932   PMID:12490567   PMID:12508227   PMID:12626757   PMID:12668638   PMID:12702154  
PMID:12736212   PMID:12736217   PMID:12808103   PMID:13129847   PMID:14550786   PMID:14573514   PMID:14573518   PMID:14614146   PMID:14667410   PMID:14727108   PMID:14976138   PMID:14978031  
PMID:15069081   PMID:15136151   PMID:15143159   PMID:15158141   PMID:15162503   PMID:15289437   PMID:15328019   PMID:15363409   PMID:15459098   PMID:15464586   PMID:15525990   PMID:15531370  
PMID:15576406   PMID:15591049   PMID:15618518   PMID:15621531   PMID:15653675   PMID:15843407   PMID:15843409   PMID:15843414   PMID:15849237   PMID:15850572   PMID:15901664   PMID:15905411  
PMID:15923624   PMID:15958514   PMID:16141072   PMID:16141073   PMID:16207763   PMID:16223478   PMID:16258075   PMID:16314491   PMID:16342201   PMID:16380715   PMID:16495310   PMID:16530167  
PMID:16556595   PMID:16556916   PMID:16602821   PMID:16611695   PMID:16624858   PMID:16677630   PMID:16680724   PMID:16684884   PMID:16783635   PMID:16870172   PMID:16894625   PMID:16971476  
PMID:16989801   PMID:16989802   PMID:17126317   PMID:17138667   PMID:17173667   PMID:17332425   PMID:17334998   PMID:17350578   PMID:17397913   PMID:17460765   PMID:17468400   PMID:17473172  
PMID:17556662   PMID:17584735   PMID:17604724   PMID:17605791   PMID:17668378   PMID:17823370   PMID:18000065   PMID:18077221   PMID:18077589   PMID:18267097   PMID:18285513   PMID:18287057  
PMID:18287559   PMID:18328475   PMID:18356246   PMID:18378906   PMID:18391012   PMID:18400219   PMID:18462699   PMID:18467625   PMID:18539269   PMID:18617694   PMID:18723448   PMID:18849322  
PMID:18985738   PMID:18990706   PMID:19035347   PMID:19075394   PMID:19084512   PMID:19168674   PMID:19464179   PMID:19576202   PMID:19592579   PMID:19661464   PMID:19706423   PMID:19727199  
PMID:19754878   PMID:19812316   PMID:19906857   PMID:19910576   PMID:19995988   PMID:20059953   PMID:20110338   PMID:20152185   PMID:20159597   PMID:20185795   PMID:20412781   PMID:20503368  
PMID:20522556   PMID:20596014   PMID:20691899   PMID:20858598   PMID:20890044   PMID:20929948   PMID:20974940   PMID:20975709   PMID:21098569   PMID:21267068   PMID:21273545   PMID:21304516  
PMID:21305474   PMID:21350214   PMID:21382375   PMID:21383175   PMID:21385575   PMID:21539829   PMID:21708977   PMID:21741963   PMID:21743013   PMID:21757651   PMID:21768366   PMID:21795281  
PMID:21873635   PMID:21890625   PMID:21897873   PMID:21898690   PMID:21983003   PMID:22072574   PMID:22116936   PMID:22174793   PMID:22192413   PMID:22203979   PMID:22223620   PMID:22421546  
PMID:22543974   PMID:22581928   PMID:22589735   PMID:22706305   PMID:22728936   PMID:22792072   PMID:22863011   PMID:22872086   PMID:22876201   PMID:22898775   PMID:22921202   PMID:22931955  
PMID:22966238   PMID:22996691   PMID:23028370   PMID:23028455   PMID:23144723   PMID:23226307   PMID:23341776   PMID:23342106   PMID:23369715   PMID:23426374   PMID:23501471   PMID:23623500  
PMID:23624311   PMID:23704920   PMID:23720040   PMID:23725765   PMID:23824573   PMID:23936153   PMID:23974038   PMID:24089201   PMID:24123507   PMID:24143284   PMID:24218595   PMID:24274029  
PMID:24324671   PMID:24335282   PMID:24565863   PMID:24582888   PMID:24626928   PMID:24650916   PMID:24651482   PMID:24677751   PMID:24705356   PMID:24811170   PMID:24858909   PMID:24996922  
PMID:25152336   PMID:25190705   PMID:25245104   PMID:25250575   PMID:25296024   PMID:25336743   PMID:25356765   PMID:25428115   PMID:25451153   PMID:25453830   PMID:25468972   PMID:25487574  
PMID:25552398   PMID:25623069   PMID:25670795   PMID:25725482   PMID:25912687   PMID:25986147   PMID:26093309   PMID:26173459   PMID:26208718   PMID:26212321   PMID:26253404   PMID:26354121  
PMID:26449264   PMID:26449528   PMID:26489465   PMID:26493106   PMID:26744331   PMID:26786475   PMID:26801181   PMID:26859351   PMID:26875865   PMID:27026076   PMID:27046536   PMID:27256596  
PMID:27320915   PMID:27396331   PMID:27582060   PMID:27606604   PMID:27633992   PMID:27992425   PMID:27997827   PMID:28164238   PMID:28167794   PMID:28287088   PMID:28302382   PMID:28346476  
PMID:28436940   PMID:28827394   PMID:28834610   PMID:29084951   PMID:29222391   PMID:29257325   PMID:29280435   PMID:29409032   PMID:29509905   PMID:29898387   PMID:30016433   PMID:30087351  
PMID:30151366   PMID:30347193   PMID:30352852   PMID:30428088   PMID:30787001   PMID:30896405   PMID:30936115   PMID:30953627   PMID:31341279   PMID:31373354   PMID:31628386   PMID:32160556  
PMID:32169553   PMID:32236096   PMID:32571845   PMID:32597756   PMID:32672536  


Genomics

Comparative Map Data
Tbx5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395119,934,581 - 120,023,285 (+)NCBI
GRCm385119,796,514 - 119,885,220 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5119,832,668 - 119,885,219 (+)EnsemblGRCm38mm10GRCm38
MGSCv375120,284,672 - 120,335,227 (+)NCBIGRCm37mm9NCBIm37
MGSCv365120,095,280 - 120,145,092 (+)NCBImm8
Celera5116,903,647 - 116,978,836 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map560.42NCBI
TBX5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12114,353,931 - 114,408,442 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl12114,353,911 - 114,408,442 (-)EnsemblGRCh38hg38GRCh38
GRCh3812114,353,911 - 114,408,708 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712114,791,735 - 114,846,247 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612113,276,118 - 113,330,630 (-)NCBINCBI36hg18NCBI36
Celera12114,419,103 - 114,473,633 (-)NCBI
Cytogenetic Map12q24.21NCBI
HuRef12111,801,135 - 111,855,628 (-)NCBIHuRef
CHM1_112114,759,933 - 114,814,388 (-)NCBICHM1_1
Tbx5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01242,059,688 - 42,148,226 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1242,097,626 - 42,148,146 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01243,909,016 - 43,998,121 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41237,956,658 - 38,004,255 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11237,820,045 - 37,867,643 (-)NCBI
Celera1238,362,373 - 38,409,445 (-)NCBICelera
Cytogenetic Map12q16NCBI
Tbx5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545516,132,975 - 16,217,953 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545516,133,130 - 16,217,894 (+)NCBIChiLan1.0ChiLan1.0
TBX5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112115,336,267 - 115,389,739 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12115,333,609 - 115,389,739 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012111,954,222 - 112,009,261 (-)NCBIMhudiblu_PPA_v0panPan3
TBX5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2611,463,653 - 11,506,446 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12611,462,541 - 11,549,699 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Tbx5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365587,408,229 - 7,454,897 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBX5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1437,773,605 - 37,824,400 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11437,772,205 - 37,826,015 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21440,161,963 - 40,260,936 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TBX5
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl11109,638,715 - 109,689,177 (-)Ensembl
ChlSab1.111109,638,694 - 109,696,619 (-)NCBI
Tbx5
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474718,307,294 - 18,348,040 (+)NCBI

Position Markers
D5Mit367  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385119,860,020 - 119,860,124UniSTSGRCm38
MGSCv375120,310,029 - 120,310,133UniSTSGRCm37
Celera5116,953,704 - 116,953,800UniSTS
Cytogenetic Map5FUniSTS
cM Map565.0UniSTS
Whitehead Genetic554.6UniSTS
Whitehead/MRC_RH51461.56UniSTS
Whitehead_YAC5 UniSTS
D5Mit424  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385119,880,432 - 119,880,564UniSTSGRCm38
MGSCv375120,330,441 - 120,330,573UniSTSGRCm37
Celera5116,974,096 - 116,974,220UniSTS
Cytogenetic Map5FUniSTS
cM Map565.0UniSTS
Whitehead Genetic554.6UniSTS
Whitehead/MRC_RH51458.1UniSTS
D5Mit425  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385119,880,441 - 119,880,564UniSTSGRCm38
MGSCv375120,330,450 - 120,330,573UniSTSGRCm37
Celera5116,974,105 - 116,974,220UniSTS
Cytogenetic Map5FUniSTS
cM Map565.0UniSTS
Whitehead Genetic554.6UniSTS
Whitehead/MRC_RH51461.56UniSTS
Whitehead_YAC5 UniSTS
Tbx5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv375120,284,946 - 120,285,031UniSTSGRCm37
Celera5116,928,930 - 116,929,015UniSTS
Cytogenetic Map5FUniSTS
cM Map565.0UniSTS
cM Map565.0UniSTS
Tbx5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5FUniSTS
Tbx5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385119,834,937 - 119,835,022UniSTSGRCm38
MGSCv375120,284,946 - 120,285,031UniSTSGRCm37
Celera5116,928,930 - 116,929,015UniSTS
Cytogenetic Map5FUniSTS
Tbx5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5FUniSTS
cM Map565.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
CRRD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526236236138457140Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554342835126924008Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)569900000132500000Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572700000140000000Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574300000132500000Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574300000132500000Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575154687119880564Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587239005121239199Mouse
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587239005121239199Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587239005121239199Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587239005121239199Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587239005121239199Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589271017124100176Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589271017146851125Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590173096124173175Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590413140124413285Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590413140124413285Mouse
9587780Afw16_mabdominal fat weight QTL 16 (mouse)Not determined592682300126682419Mouse
1301974Chab7_mcholesterol absorption 7 (mouse)Not determined595085348129085464Mouse
1357644Egrd1_mearly growth rate, direct effect 1 (mouse)Not determined595286714129286920Mouse
1558774Lith17_mlithogenic gene 17 (mouse)Not determined595317683129317856Mouse
10402486Dipa1_mdrug induced psychomotor activation 1 (mouse)Not determined595317683129317856Mouse
13464244Ahl19_mage related hearing loss, early onset 19 (mouse)595317683129317856Mouse
1300940Actd3_mactivity-distance traveled 3 (mouse)Not determined596172519130172667Mouse
1300659Pcd8ts1_mp-glycoprotein positive CD8 T cell subset 1 (mouse)Not determined596883692130883925Mouse
1301858Smdq1_msegregation of mitochondrial DNA QTL 1 (mouse)Not determined596883692130883925Mouse
4141519Hmtb5_mhemostasis and thrombosis bleeding time 5 (mouse)Not determined99801563126805880Mouse
12904945Tammq2_mtibialis anterior muscle mass QTL 2 (mouse)5100527900134527900Mouse
12904959Smmq1_msoleus muscle mass QTL 1 (mouse)5100527900134527900Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101194514135194514Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101725767135725963Mouse
14746986Manh58_mmandible shape 58 (mouse)5102308218136308218Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102806972136807131Mouse
11528550Sluc33_msusceptibility to lung cancer 33 (mouse)5104239005120573921Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104435822138557193Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104567876138567876Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107829235141829348Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107829235141829348Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107829235141829348Mouse
4141139Hmtb4_mhemostasis and thrombosis rebleeding time 4 (mouse)Not determined108614643126805880Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109090176143090317Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109090176143090317Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109090758139133150Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109362284143362395Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113172519138557193Mouse
1357662Lprq4_mlipoprotein QTL 4 (mouse)Not determined5113883692129555542Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115128044149128176Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115128044149128176Mouse
1301857Bglq14_mbody growth late QTL 14 (mouse)Not determined5118920110151834684Mouse
10412191Bbaa24_mB.burgdorferi-associated arthritis 24 (mouse)Not determined5119806972141714711Mouse
4141081Nidd7k_mNidd7 on KK-A (mouse)Not determined119806972149423861Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:640
Count of miRNA genes:377
Interacting mature miRNAs:457
Transcripts:ENSMUST00000018407
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000018407   ⟹   ENSMUSP00000018407
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5119,834,663 - 119,885,219 (+)Ensembl
RefSeq Acc Id: ENSMUST00000202504   ⟹   ENSMUSP00000143828
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5119,836,155 - 119,845,110 (+)Ensembl
RefSeq Acc Id: ENSMUST00000202723   ⟹   ENSMUSP00000144418
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5119,832,668 - 119,840,886 (+)Ensembl
RefSeq Acc Id: NM_011537   ⟹   NP_035667
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395119,972,728 - 120,023,283 (+)NCBI
GRCm385119,834,663 - 119,885,218 (+)NCBI
MGSCv375120,284,672 - 120,335,227 (+)RGD
Celera5116,903,647 - 116,978,836 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006530279   ⟹   XP_006530342
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395119,972,742 - 120,023,285 (+)NCBI
GRCm385119,834,679 - 119,885,220 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006530280   ⟹   XP_006530343
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395119,970,733 - 120,023,285 (+)NCBI
GRCm385119,832,668 - 119,885,220 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006530281   ⟹   XP_006530344
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395119,970,241 - 120,023,285 (+)NCBI
GRCm385119,832,176 - 119,885,220 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006530282   ⟹   XP_006530345
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395119,934,714 - 120,023,285 (+)NCBI
GRCm385119,796,647 - 119,885,220 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006530283   ⟹   XP_006530346
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395119,934,581 - 120,023,285 (+)NCBI
GRCm385119,796,514 - 119,885,220 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011248191   ⟹   XP_011246493
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395119,973,850 - 120,023,285 (+)NCBI
GRCm385119,835,781 - 119,885,220 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_035667   ⟸   NM_011537
- UniProtKB: P70326 (UniProtKB/Swiss-Prot),   Q5CZX7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006530346   ⟸   XM_006530283
- Peptide Label: isoform X2
- UniProtKB: P70326 (UniProtKB/Swiss-Prot),   Q5CZX7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006530345   ⟸   XM_006530282
- Peptide Label: isoform X2
- UniProtKB: P70326 (UniProtKB/Swiss-Prot),   Q5CZX7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006530344   ⟸   XM_006530281
- Peptide Label: isoform X2
- UniProtKB: P70326 (UniProtKB/Swiss-Prot),   Q5CZX7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006530343   ⟸   XM_006530280
- Peptide Label: isoform X2
- UniProtKB: P70326 (UniProtKB/Swiss-Prot),   Q5CZX7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006530342   ⟸   XM_006530279
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011246493   ⟸   XM_011248191
- Peptide Label: isoform X2
- UniProtKB: P70326 (UniProtKB/Swiss-Prot),   Q5CZX7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000143828   ⟸   ENSMUST00000202504
RefSeq Acc Id: ENSMUSP00000144418   ⟸   ENSMUST00000202723
RefSeq Acc Id: ENSMUSP00000018407   ⟸   ENSMUST00000018407

Promoters
RGD ID:6887846
Promoter ID:EPDNEW_M7374
Type:single initiation site
Name:Tbx5_2
Description:Mus musculus T-box 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M7375  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385119,834,618 - 119,834,678EPDNEW
RGD ID:6887848
Promoter ID:EPDNEW_M7375
Type:initiation region
Name:Tbx5_1
Description:Mus musculus T-box 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M7374  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385119,835,143 - 119,835,203EPDNEW
RGD ID:6847955
Promoter ID:MM_ACW:39228
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:TBX5.BSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365120,285,106 - 120,285,606 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:102541 AgrOrtholog
Ensembl Genes ENSMUSG00000018263 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000018407 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000143828 UniProtKB/TrEMBL
  ENSMUSP00000144418 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000018407 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000202504 UniProtKB/TrEMBL
  ENSMUST00000202723 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T-box_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_T-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_T-box_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21388 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:102541 ENTREZGENE
NCBI Gene 21388 ENTREZGENE
PANTHER PTHR11267 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam T-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tbx5 PhenoGen
PRINTS TBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TBOX_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBOX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBOX_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART TBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49417 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.103636 ENTREZGENE
UniProt A0A0J9YTS5_MOUSE UniProtKB/TrEMBL
  A0A0J9YUZ8_MOUSE UniProtKB/TrEMBL
  P70326 ENTREZGENE
  Q5CZX7 ENTREZGENE, UniProtKB/TrEMBL
  Q8BLK4_MOUSE UniProtKB/TrEMBL
  TBX5_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q9R003 UniProtKB/Swiss-Prot