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Gene: Fbxl4 (F-box and leucine-rich repeat protein 4) Mus musculus
Symbol: Fbxl4
Name: F-box and leucine-rich repeat protein 4
Description: Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to localize to SCF ubiquitin ligase complex; mitochondrial intermembrane space; and nuclear speck. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 13. Orthologous to human FBXL4 (F-box and leucine rich repeat protein 4); INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4732456I21; AI836810; F-box/LRR-repeat protein 4; FBL4; FBL5
Homo sapiens (human) : FBXL4 (F-box and leucine rich repeat protein 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fbxl4 (F-box and leucine-rich repeat protein 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxl4 (F-box and leucine rich repeat protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXL4 (F-box and leucine rich repeat protein 4)
Canis lupus familiaris (dog) : FBXL4 (F-box and leucine rich repeat protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxl4 (F-box and leucine rich repeat protein 4)
Sus scrofa (pig) : FBXL4 (F-box and leucine rich repeat protein 4)
Chlorocebus sabaeus (African green monkey) : FBXL4 (F-box and leucine rich repeat protein 4)
Heterocephalus glaber (naked mole-rat) : Fbxl4 (F-box and leucine rich repeat protein 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl422,357,543 - 22,434,091 (+)EnsemblGRCm38mm10GRCm38
GRCm38422,357,526 - 22,434,091 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37422,284,712 - 22,361,193 (+)NCBIGRCm37mm9NCBIm37
MGSCv36422,448,400 - 22,524,881 (+)NCBImm8
Celera422,111,884 - 22,188,205 (+)NCBICelera
Cytogenetic Map4A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fbxl4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313924
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.