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Gene: LRP8 (LDL receptor related protein 8) Homo sapiens
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Symbol: LRP8
Name: LDL receptor related protein 8
Description: Exhibits very-low-density lipoprotein particle receptor activity. Involved in endocytosis. Localizes to the caveola and receptor complex. Implicated in Alzheimer's disease; coronary artery disease; dementia; myocardial infarction; and schizophrenia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ApoE receptor 2; APOER2; apolipoprotein E receptor 2; HSZ75190; low density lipoprotein receptor-related protein 8, apolipoprotein e receptor; low-density lipoprotein receptor-related protein 8; LRP-8; MCI1; RP5-1024G6.8
Orthologs:
Mus musculus (house mouse) : Lrp8 (low density lipoprotein receptor-related protein 8, apolipoprotein e receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lrp8 (LDL receptor related protein 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lrp8 (LDL receptor related protein 8)
Pan paniscus (bonobo/pygmy chimpanzee) : LRP8 (LDL receptor related protein 8)
Canis lupus familiaris (dog) : LRP8 (LDL receptor related protein 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lrp8 (LDL receptor related protein 8)
Sus scrofa (pig) : LRP8 (LDL receptor related protein 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38153,242,364 - 53,328,070 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37153,708,036 - 53,793,821 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36153,483,800 - 53,566,409 (-)NCBINCBI36hg18NCBI36
Celera151,999,058 - 52,081,130 (-)NCBI
Cytogenetic Map1p32.3NCBI
HuRef151,823,713 - 51,909,108 (-)NCBIHuRef
CHM1_1153,825,039 - 53,910,558 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on LRP8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313932
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.