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Gene: LIMS1 (LIM zinc finger domain containing 1) Homo sapiens
Symbol: LIMS1
Name: LIM zinc finger domain containing 1
Description: Exhibits protein kinase binding activity and zinc ion binding activity. Involved in several processes, including positive regulation of NIK/NF-kappaB signaling; positive regulation of cell-substrate adhesion; and regulation of gene expression. Localizes to the cell-cell junction; focal adhesion; and perinuclear region of cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: LIM and senescent cell antigen-like domains 1; LIM and senescent cell antigen-like-containing domain protein 1; LIM-type zinc finger domains 1; particularly interesting new Cys-His protein 1; PINCH; PINCH-1; PINCH1; renal carcinoma antigen NY-REN-48; senescent cell antigen
Mus musculus (house mouse) : Lims1 (LIM and senescent cell antigen-like domains 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lims1 (LIM zinc finger domain containing 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lims1 (LIM zinc finger domain containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LIMS1 (LIM zinc finger domain containing 1)
Canis lupus familiaris (dog) : LIMS1 (LIM zinc finger domain containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lims1 (LIM zinc finger domain containing 1)
Sus scrofa (pig) : LIMS1 (LIM zinc finger domain containing 1)
Chlorocebus sabaeus (green monkey) : LIMS1 (LIM zinc finger domain containing 1)
Heterocephalus glaber (naked mole-rat) : Lims1 (LIM zinc finger domain containing 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2108,534,355 - 108,687,246 (+)Ensembl
GRCh382108,533,671 - 108,687,246 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372109,150,811 - 109,303,702 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362108,571,199 - 108,667,321 (+)NCBINCBI36hg18NCBI36
Build 342108,663,284 - 108,759,405NCBI
Celera2103,464,751 - 103,615,238 (+)NCBI
Cytogenetic Map2q12.3NCBI
HuRef2102,803,913 - 102,903,724 (+)NCBIHuRef
CHM1_12109,154,977 - 109,307,968 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LIMS1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313937
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.