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Gene: STAT4 (signal transducer and activator of transcription 4) Homo sapiens
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Symbol: STAT4
Name: signal transducer and activator of transcription 4
CRRD ID: 1313964
Description: Exhibits identical protein binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; hematopoietic stem cell homeostasis; and positive regulation of transcription by RNA polymerase II. Predicted to localize to cytosol and nuclear chromatin. Implicated in several diseases, including IgA glomerulonephritis; autoimmune disease (multiple); dermatomyositis; genital herpes; and systemic scleroderma (multiple). Biomarker of Sezary's disease; cholesteatoma; and viral hepatitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: signal transducer and activator of transcription 4 variant 3; SLEB11
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2191,029,576 - 191,151,596 (-)EnsemblGRCh38hg38GRCh38
GRCh382191,029,576 - 191,172,684 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372191,894,302 - 192,037,404 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362191,602,551 - 191,724,170 (-)NCBINCBI36hg18NCBI36
Build 342191,719,811 - 191,841,431NCBI
Celera2185,488,908 - 185,610,548 (-)NCBI
Cytogenetic Map2q32.2-q32.3NCBI
HuRef2183,753,956 - 183,875,743 (-)NCBIHuRef
CHM1_12191,900,128 - 192,022,113 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
 
More on STAT4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313964
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.