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Gene: NUDT21 (nudix hydrolase 21) Homo sapiens
Symbol: NUDT21
Name: nudix hydrolase 21
Description: Exhibits histone deacetylase binding activity; mRNA 3'-UTR AU-rich region binding activity; and protein homodimerization activity. Contributes to RNA binding activity. Involved in several processes, including messenger ribonucleoprotein complex assembly; pre-mRNA cleavage required for polyadenylation; and regulation of mRNA metabolic process. Localizes to the centriolar satellite; cytoplasm; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CFIM25; cleavage and polyadenylation specific factor 5, 25 kD subunit; cleavage and polyadenylation specific factor 5, 25 kDa; cleavage and polyadenylation specificity factor 25 kDa subunit; cleavage and polyadenylation specificity factor subunit 5; cleavage factor Im complex 25 kDa subunit; CPSF 25 kDa subunit; CPSF5; DKFZp686H1588; nucleoside diphosphate-linked moiety X motif 21; nudix (nucleoside diphosphate linked moiety X)-type motif 21; nudix motif 21; pre-mRNA cleavage factor Im (25kD); pre-mRNA cleavage factor Im 25 kDa subunit; pre-mRNA cleavage factor Im 68 kDa subunit; pre-mRNA cleavage factor Im, 25kD subunit
Mus musculus (house mouse) : Nudt21 (nudix (nucleoside diphosphate linked moiety X)-type motif 21)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nudt21 (nudix hydrolase 21)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nudt21 (nudix hydrolase 21)
Pan paniscus (bonobo/pygmy chimpanzee) : NUDT21 (nudix hydrolase 21)
Canis lupus familiaris (dog) : NUDT21 (nudix hydrolase 21)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nudt21 (nudix hydrolase 21)
Sus scrofa (pig) : NUDT21 (nudix hydrolase 21)
more info ...
Related Pseudogenes: NUDT21P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381656,429,133 - 56,451,332 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371656,463,048 - 56,485,261 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361655,020,549 - 55,042,762 (-)NCBINCBI36hg18NCBI36
Build 341655,020,549 - 55,042,762NCBI
Celera1640,961,067 - 40,983,280 (-)NCBI
Cytogenetic Map16q13NCBI
HuRef1642,333,427 - 42,355,686 (-)NCBIHuRef
CHM1_11657,870,031 - 57,892,257 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NUDT21
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313996
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.