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Gene: NUDT21 (nudix hydrolase 21) Homo sapiens
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Symbol: NUDT21
Name: nudix hydrolase 21
Description: Exhibits histone deacetylase binding activity; mRNA 3'-UTR AU-rich region binding activity; and protein homodimerization activity. Contributes to RNA binding activity. Involved in several processes, including messenger ribonucleoprotein complex assembly; pre-mRNA cleavage required for polyadenylation; and regulation of mRNA metabolic process. Localizes to the centriolar satellite; cytoplasm; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CFIM25; cleavage and polyadenylation specific factor 5, 25 kD subunit; cleavage and polyadenylation specific factor 5, 25 kDa; cleavage and polyadenylation specificity factor 25 kDa subunit; cleavage and polyadenylation specificity factor subunit 5; cleavage factor Im complex 25 kDa subunit; CPSF 25 kDa subunit; CPSF5; DKFZp686H1588; nucleoside diphosphate-linked moiety X motif 21; nudix (nucleoside diphosphate linked moiety X)-type motif 21; nudix motif 21; pre-mRNA cleavage factor Im (25kD); pre-mRNA cleavage factor Im 25 kDa subunit; pre-mRNA cleavage factor Im 68 kDa subunit; pre-mRNA cleavage factor Im, 25kD subunit
Orthologs:
Mus musculus (house mouse) : Nudt21 (nudix (nucleoside diphosphate linked moiety X)-type motif 21)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nudt21 (nudix hydrolase 21)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nudt21 (nudix hydrolase 21)
Pan paniscus (bonobo/pygmy chimpanzee) : NUDT21 (nudix hydrolase 21)
Canis lupus familiaris (dog) : NUDT21 (nudix hydrolase 21)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nudt21 (nudix hydrolase 21)
Sus scrofa (pig) : NUDT21 (nudix hydrolase 21)
more info ...
Related Pseudogenes: NUDT21P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381656,429,133 - 56,451,332 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371656,463,048 - 56,485,261 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361655,020,549 - 55,042,762 (-)NCBINCBI36hg18NCBI36
Build 341655,020,549 - 55,042,762NCBI
Celera1640,961,067 - 40,983,280 (-)NCBI
Cytogenetic Map16q13NCBI
HuRef1642,333,427 - 42,355,686 (-)NCBIHuRef
CHM1_11657,870,031 - 57,892,257 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NUDT21
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313996
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.