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Gene: CPSF3 (cleavage and polyadenylation specific factor 3) Homo sapiens
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Symbol: CPSF3
Name: cleavage and polyadenylation specific factor 3
Description: Predicted to have 5'-3' exonuclease activity; RNA binding activity; and endoribonuclease activity. Involved in mRNA 3'-end processing by stem-loop binding activity and cleavage. Localizes to the mRNA cleavage and polyadenylation specificity factor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cleavage and polyadenylation specific factor 3, 73kDa; cleavage and polyadenylation specificity factor 3; cleavage and polyadenylation specificity factor 73 kDa subunit; cleavage and polyadenylation specificity factor subunit 3; CPSF; CPSF 73 kDa subunit; CPSF-73; CPSF73; mRNA 3'-end-processing endonuclease CPSF-73; YSH1
Orthologs:
Mus musculus (house mouse) : Cpsf3 (cleavage and polyadenylation specificity factor 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cpsf3 (cleavage and polyadenylation specific factor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cpsf3 (cleavage and polyadenylation specific factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CPSF3 (cleavage and polyadenylation specific factor 3)
Canis lupus familiaris (dog) : CPSF3 (cleavage and polyadenylation specific factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cpsf3 (cleavage and polyadenylation specific factor 3)
Sus scrofa (pig) : CPSF3 (cleavage and polyadenylation specific factor 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3829,423,537 - 9,473,110 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3729,563,666 - 9,613,239 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3629,481,319 - 9,530,678 (+)NCBINCBI36hg18NCBI36
Build 3429,514,465 - 9,563,825NCBI
Celera29,475,764 - 9,525,116 (+)NCBI
Cytogenetic Map2p25.1NCBI
HuRef29,409,149 - 9,458,762 (+)NCBIHuRef
CHM1_129,493,101 - 9,542,657 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CPSF3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1313998
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.