Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: PINK1 (PTEN induced kinase 1) Homo sapiens
Analyze
Symbol: PINK1
Name: PTEN induced kinase 1
CRRD ID: 1314001
Description: Exhibits several functions, including ATP binding activity; enzyme binding activity; and protein kinase activity. Involved in several processes, including protein localization to mitochondrion; regulation of intracellular signal transduction; and regulation of mitochondrion organization. Localizes to several cellular components, including astrocyte projection; mitochondrial envelope; and perinuclear region of cytoplasm. Implicated in Parkinson's disease and Parkinson's disease 6.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BRPK; FLJ27236; PARK6; Parkinson disease (autosomal recessive) 6; protein kinase BRPK; PTEN induced putative kinase 1; PTEN-induced putative kinase protein 1; serine/threonine-protein kinase PINK1, mitochondrial
Orthologs:
Mus musculus (house mouse) : Pink1 (PTEN induced putative kinase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pink1 (PTEN induced kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pink1 (PTEN induced kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PINK1 (PTEN induced kinase 1)
Canis lupus familiaris (dog) : PINK1 (PTEN induced kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pink1 (PTEN induced kinase 1)
Sus scrofa (pig) : PINK1 (PTEN induced kinase 1)
Chlorocebus sabaeus (African green monkey) : PINK1 (PTEN induced kinase 1)
Heterocephalus glaber (naked mole-rat) : Pink1 (PTEN induced kinase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl120,633,458 - 20,651,511 (+)EnsemblGRCh38hg38GRCh38
GRCh38120,633,458 - 20,651,511 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37120,959,948 - 20,978,004 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36120,832,535 - 20,850,591 (+)NCBINCBI36hg18NCBI36
Build 34120,705,253 - 20,723,309NCBI
Celera119,284,119 - 19,302,182 (+)NCBI
Cytogenetic Map1p36.12NCBI
HuRef119,206,074 - 19,224,136 (+)NCBIHuRef
CHM1_1121,070,747 - 21,088,823 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PINK1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314001
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-10-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.