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Gene: Pink1 (PTEN induced putative kinase 1) Mus musculus
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Symbol: Pink1
Name: PTEN induced putative kinase 1
Description: Exhibits ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in several processes, including negative regulation of apoptotic process; positive regulation of cellular protein metabolic process; and regulation of gene expression. Localizes to the mitochondrial inner membrane. Used to study Parkinson's disease 6. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 6. Is expressed in cardiovascular system; nervous system; sensory organ; and testis. Orthologous to human PINK1 (PTEN induced kinase 1); PARTICIPATES IN altered mitochondrial autophagy pathway; mitochondrial autophagy pathway; Parkinson's disease pathway; INTERACTS WITH 1,1-dichloroethene; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1190006F07Rik; AU042772; AW557854; BRPK; mFLJ00387; PTEN-induced putative kinase protein 1; serine/threonine-protein kinase PINK1, mitochondrial
Orthologs:
Homo sapiens (human) : PINK1 (PTEN induced kinase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pink1 (PTEN induced kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pink1 (PTEN induced kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PINK1 (PTEN induced kinase 1)
Canis lupus familiaris (dog) : PINK1 (PTEN induced kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pink1 (PTEN induced kinase 1)
Sus scrofa (pig) : PINK1 (PTEN induced kinase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm384138,313,409 - 138,326,296 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374137,869,324 - 137,882,211 (-)NCBIGRCm37mm9NCBIm37
MGSCv364137,585,488 - 137,598,347 (-)NCBImm8
Celera4140,093,554 - 140,110,379 (-)NCBICelera
Cytogenetic Map4 D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pink1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314002
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.