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Gene: INPP5F (inositol polyphosphate-5-phosphatase F) Homo sapiens
Symbol: INPP5F
Name: inositol polyphosphate-5-phosphatase F
Description: Exhibits phosphatidylinositol phosphate 4-phosphatase activity; phosphatidylinositol phosphate 5-phosphatase activity; and protein homodimerization activity. Involved in several processes, including negative regulation of tyrosine phosphorylation of STAT protein; phosphatidylinositol dephosphorylation; and positive regulation of receptor recycling. Localizes to the cytoplasmic vesicle and intracellular membrane-bounded organelle. Colocalizes with the clathrin-coated pit.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ13081; hSAC2; inositol polyphosphate 5-phosphatase F; KIAA0966; MGC131851; MGC59773; MSTP007; MSTPO47; phosphatidylinositide phosphatase SAC2; Sac domain-containing inositol phosphatase 2; sac domain-containing phosphoinositide 4-phosphatase 2; sac domain-containing phosphoinositide 5-phosphatase 2; SAC2
Mus musculus (house mouse) : Inpp5f (inositol polyphosphate-5-phosphatase F)  MGI  Alliance
Rattus norvegicus (Norway rat) : Inpp5f (inositol polyphosphate-5-phosphatase F)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Inpp5f (inositol polyphosphate-5-phosphatase F)
Pan paniscus (bonobo/pygmy chimpanzee) : INPP5F (inositol polyphosphate-5-phosphatase F)
Canis lupus familiaris (dog) : INPP5F (inositol polyphosphate-5-phosphatase F)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Inpp5f (inositol polyphosphate-5-phosphatase F)
Sus scrofa (pig) : INPP5F (inositol polyphosphate-5-phosphatase F)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3810119,704,395 - 119,830,482 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710121,485,559 - 121,588,663 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610121,475,599 - 121,578,649 (+)NCBINCBI36hg18NCBI36
Celera10115,216,680 - 115,319,730 (+)NCBI
Cytogenetic Map10q26.11NCBI
HuRef10115,115,057 - 115,217,590 (+)NCBIHuRef
CHM1_110121,770,489 - 121,873,582 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on INPP5F
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314013
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.