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Gene: ZNF451 (zinc finger protein 451) Homo sapiens
Symbol: ZNF451
Name: zinc finger protein 451
Description: Exhibits SUMO ligase activity and transcription corepressor activity. Involved in negative regulation of nitrogen compound metabolic process; negative regulation of transforming growth factor beta receptor signaling pathway; and protein sumoylation. Localizes to the nucleus. Predicted to colocalize with the histone methyltransferase complex; INTERACTS WITH (-)-demecolcine; 2,2',4,4'-Tetrabromodiphenyl ether; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: coactivator for steroid receptors; COASTER; dJ417I1.1; E3 SUMO-protein ligase ZNF451; E3 SUMO-protein transferase ZNF451; FLJ23421; FLJ53246; FLJ90693; KIAA0576; KIAA1702; MGC26701
Mus musculus (house mouse) : Zfp451 (zinc finger protein 451)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zfp451 (zinc finger protein 451)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Znf451 (zinc finger protein 451)
Pan paniscus (bonobo/pygmy chimpanzee) : ZNF451 (zinc finger protein 451)
Canis lupus familiaris (dog) : ZNF451 (zinc finger protein 451)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Znf451 (zinc finger protein 451)
Sus scrofa (pig) : ZNF451 (zinc finger protein 451)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38657,088,970 - 57,170,305 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37656,954,808 - 57,035,103 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36657,062,787 - 57,143,057 (+)NCBINCBI36hg18NCBI36
Build 34657,062,786 - 57,142,958NCBI
Celera658,617,929 - 58,698,197 (+)NCBI
Cytogenetic Map6p12.1NCBI
HuRef656,788,725 - 56,869,155 (+)NCBIHuRef
CHM1_1656,955,130 - 57,035,424 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ZNF451
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314152
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.