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Gene: ZNF451 (zinc finger protein 451) Homo sapiens
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Symbol: ZNF451
Name: zinc finger protein 451
Description: Exhibits SUMO ligase activity and transcription corepressor activity. Involved in negative regulation of nitrogen compound metabolic process; negative regulation of transforming growth factor beta receptor signaling pathway; and protein sumoylation. Localizes to the nucleus. Predicted to colocalize with the histone methyltransferase complex; INTERACTS WITH (-)-demecolcine; 2,2',4,4'-Tetrabromodiphenyl ether; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: coactivator for steroid receptors; COASTER; dJ417I1.1; E3 SUMO-protein ligase ZNF451; E3 SUMO-protein transferase ZNF451; FLJ23421; FLJ53246; FLJ90693; KIAA0576; KIAA1702; MGC26701
Orthologs:
Mus musculus (house mouse) : Zfp451 (zinc finger protein 451)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zfp451 (zinc finger protein 451)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Znf451 (zinc finger protein 451)
Pan paniscus (bonobo/pygmy chimpanzee) : ZNF451 (zinc finger protein 451)
Canis lupus familiaris (dog) : ZNF451 (zinc finger protein 451)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Znf451 (zinc finger protein 451)
Sus scrofa (pig) : ZNF451 (zinc finger protein 451)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38657,088,970 - 57,170,305 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37656,954,808 - 57,035,103 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36657,062,787 - 57,143,057 (+)NCBINCBI36hg18NCBI36
Build 34657,062,786 - 57,142,958NCBI
Celera658,617,929 - 58,698,197 (+)NCBI
Cytogenetic Map6p12.1NCBI
HuRef656,788,725 - 56,869,155 (+)NCBIHuRef
CHM1_1656,955,130 - 57,035,424 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ZNF451
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314152
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.