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Gene: GNS (glucosamine (N-acetyl)-6-sulfatase) Homo sapiens
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Symbol: GNS
Name: glucosamine (N-acetyl)-6-sulfatase
Description: Exhibits sulfuric ester hydrolase activity. Predicted to be involved in keratan sulfate catabolic process and neutrophil degranulation. Localizes to the extracellular exosome. Implicated in mucopolysaccharidosis III.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: G6S; glucosamine -6-sulfatase; glucosamine-6-sulfatase; MGC21274; N-acetylglucosamine-6-sulfatase
Orthologs:
Mus musculus (house mouse) : Gns (glucosamine (N-acetyl)-6-sulfatase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gns (glucosamine (N-acetyl)-6-sulfatase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gns (glucosamine (N-acetyl)-6-sulfatase)
Pan paniscus (bonobo/pygmy chimpanzee) : GNS (glucosamine (N-acetyl)-6-sulfatase)
Canis lupus familiaris (dog) : GNS (glucosamine (N-acetyl)-6-sulfatase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gns (glucosamine (N-acetyl)-6-sulfatase)
Sus scrofa (pig) : GNS (glucosamine (N-acetyl)-6-sulfatase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381264,713,449 - 64,759,406 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371265,107,222 - 65,153,226 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361263,393,489 - 63,439,479 (-)NCBINCBI36hg18NCBI36
Build 341263,393,490 - 63,439,479NCBI
Celera1264,772,049 - 64,818,041 (-)NCBI
Cytogenetic Map12q14.3NCBI
HuRef1262,157,915 - 62,203,861 (-)NCBIHuRef
CHM1_11265,074,143 - 65,120,149 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on GNS
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314172
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.