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Gene: Gns (glucosamine (N-acetyl)-6-sulfatase) Mus musculus
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Symbol: Gns
Name: glucosamine (N-acetyl)-6-sulfatase
Description: Predicted to have N-acetylglucosamine-6-sulfatase activity; glycosaminoglycan binding activity; and sulfate binding activity. Predicted to be involved in glycosaminoglycan metabolic process. Localizes to the lysosome. Used to study mucopolysaccharidosis III. Human ortholog(s) of this gene implicated in mucopolysaccharidosis III. Is expressed in several structures, including eye; nervous system; skeleton; and spleen primordium. Orthologous to human GNS (glucosamine (N-acetyl)-6-sulfatase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; isoprenaline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610016K11Rik; AU042285; C87209; G6S; glucosamine-6-sulfatase; N-acetylglucosamine-6-sulfatase; N28088
Orthologs:
Homo sapiens (human) : GNS (glucosamine (N-acetyl)-6-sulfatase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gns (glucosamine (N-acetyl)-6-sulfatase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gns (glucosamine (N-acetyl)-6-sulfatase)
Pan paniscus (bonobo/pygmy chimpanzee) : GNS (glucosamine (N-acetyl)-6-sulfatase)
Canis lupus familiaris (dog) : GNS (glucosamine (N-acetyl)-6-sulfatase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gns (glucosamine (N-acetyl)-6-sulfatase)
Sus scrofa (pig) : GNS (glucosamine (N-acetyl)-6-sulfatase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3810121,365,090 - 121,397,254 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710120,802,146 - 120,834,301 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610120,768,150 - 120,800,305 (+)NCBImm8
Celera10123,737,286 - 123,777,799 (+)NCBICelera
Cytogenetic Map10 D2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gns
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314173
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.